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Automated Library Synthesis (ALiS) System

Read independent reviews on Automated Library Synthesis (ALiS) System from Particle Works on SelectScience ....

Anti Dispersion Technology , Encapsulation Efficiency ,

Novel Curcumin Derivative-Decorated Ultralong-Circulating Paclitaxel N

Novel Curcumin Derivative-Decorated Ultralong-Circulating Paclitaxel Nanoparticles: A Novel Delivery System with Superior Anticancer Efficacy and Safety ....

United States , United Kingdom , Shimadzu Iraffinity , Laboratory Animals , Sparford Beijing Biotechnology Co Ltd , Laboratory Animal Production License No , University Laboratory Animal , Chinese Academy Of Sciences , Animal Center , Soleboro Technology Co Ltd , Luzhou Renkang Biotechnology Co Ltd , Chengdu Dashuo Laboratory Animal Co Ltd , Cell Bank Center , Pharmacokinetic Parameters In Rats Following Injection Administration , Laboratory Animal Use , Experimental Animal Center , Shanghai Aladdin Biochemical Technology Co Ltd , Lipoid Gmbh , Chinese Academy , Laboratory Animal Use License , Female Sprague Dawley , Southwest Medical University , Laboratory Animal License , Laboratory Animal Production License , Southwest Medical , Animal Experiments ,

Overcoming doxorubicin resistance in breast cancer

Overcoming doxorubicin resistance in breast cancer
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United States , United Kingdom , Becton Dickinson Facscalibur , Ningbo Scientz Biotechnology Co Ltd , A Peptide Co Ltd Shanghai , Shanghai Beyotime Biotechnology Co , Huafeng United Technology Co , Aladdin Regent Co , Palm Oil , Beijing Huafeng United Technology , Aladdin Regent , Life Technologies , Shanghai Beyotime Biotechnology , Type Culture Collection , Chinese Academy , Bruker Instruments , Zetasizer Nano , Malvern Instruments , Drug Release , Becton Dickinson , Mitotracker Green , Membrane Potential Assay , Reactive Oxygen Species , P Gp Efflux , Encapsulation Efficiency , Standard Deviation ,

Novel nanoparticle biocompatibility and antitumor activity.

Conclusions
In the present study, CNPs were successfully prepared; they had a relatively small and uniform particle size, and stable physical and chemical properties. CNPs can increase the Cur solubility, and β-CD block the drugs in mesoporous silicon channels and graft cRGD as targeting groups recognized by academia. And combined with EPR effect, we can achieve better tumor targeting. Moreover, CNP carriers demonstrated a low hemolysis rate and ideal cell compatibility, and they did not cause any obvious irritative damage to the intact skin. CNPs played an anti-cancer role by inducing apoptosis of S phase and G2/M phase cells. In vitro and in vivo experiments also showed that CNPs had good tumor-targeting ability and anti-tumor activity. In conclusion, CNPs have an ideal biosafety and therapeutic effect for recurrent BC. ....

United States , New Zealand , Eteläuomen Läi , Dnc Dpc , Aladdin Reagent Co Ltd Shanghai , Sinopharm Chemical Reagent Co Ltd Shanghai , Greenbird Inc , Zhengzhou University , Meryer Chemical Technology Co Ltd Shanghai , Stem Cell Bank , Experimental Animal Center , Aldrich China Co Ltd Shanghai , Meloney Biotechnology Co Ltd Dalian , National Institutes Of Health , Chinese Academy Of Sciences , Asia Reagent Co Ltd Chengdu , Ethical Committee Of Zhengzhou University , Anhui Muweixing Technology Co Ltd Hefei , Modified Eagle Medium , Chinese Academy , Ethical Committee , National Institutes , Zetasizer Nano , Loading Content , Encapsulation Efficiency , Skin Irritation Tests ,

[Full text] Pterostilbene Nanoparticles Downregulate Hypoxia-Inducible Factors in

E) PSN1:4:4, (
F) PSN1:8:8. The direction of the arrows represents the position of the hydrogen bond between PTS and EE-PVA.
We also investigated the hydro-binding of PTS and nanocarriers using
1H-NMR spectra (Figure 4B–F). We observed several characteristic protons in the PTS
1H-NMR spectra, such as aromatic protons in the regions of δ6.3–7.5 ppm, methyl protons at δ3.8, and hydroxyl protons at δ9.6 (Figure 4B). In addition, Figure 4 shows that the integrated intensity at δ9.6 ppm of PTS was observed in PSN with excipient ratios of 1:2:2 (Figure 4D) and 1:4:4 (Figure 4E); however, PSN with a 1:8:8 excipient ratio did not display an integrated signal (Figure 4F). Moreover, we observed that in the spectrum of PSN that had an excipient ratio of 1:8:8, these protons had shifted and the hydroxyl proton had disappeared (Table 2 and Figure 5). These results demonstrated that EE100/PVA effectively encapsulated PTS via intermolecular hydrogen-bonding and formed a ....

United States , United Kingdom , Comunidad Autonoma De Cataluna , Franklin Lakes , Toyo Roshi Kaisha , Determination Of Hydrogen , System Oxford Instrument Co , Microsoft Office , Food Industry Research , Microsoft Corporation , Biotek Instruments Inc , Hydrogen Bonding , Cell Signaling Technology , Otsuka Electronics , Development Institute Hsinchu , Varian Mercury Plus , Amorphous Transformation , Pterostilbene Nanoparticles , Pterostilbene Content , High Performance Liquid , Lachrom Elite , Encapsulation Efficiency , Development Institute , Himedia Laboratories , Thermo Fisher Scientific , Biological Industries ,