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Potential treatment approach kills lymphoma while sparing healthy cells


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IMAGE: A heavy layer of glycans, seen here in green, cover immune cells and provide a way to target cancer-specific markers in the body.
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Credit: Image courtesy of Senlian Hong, Wu Lab at Scripps Research
LA JOLLA, CA Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.
The new approach uses natural cancer-targeting immune cells, known as natural killer cells, that have been modified to selectively target lymphoma. As described in their study, published in the journal
Angewandte Chemie, the modified natural killer cells brought about a dramatic reduction of lymphoma in a mouse. ....

United States , Bo Cheng , Emily Rodrigues , Jie Li , Digantkumar Chapla , Henrik Clausen , Yujie Shi , Yuanhui Ma , Weiqian Cao , Chenhua Yu , Angewandte Chemie , Peng Wu , Senlian Hong , Matthew Scott Macauley , James Paulson , Xing Chen , Peng Wang , Yoshiki Narimatsu , Scripps Research , National Institutes Of Health , Danish National Research Foundation , Department Of Molecular Medicine At Scripps Research , Molecular Medicine , Ida Green Professor , John Yates , Kelly Moremen ,