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Key Takeaways in the Treatment of Advanced RCC From KCRS 2023

Robert Motzer, MD, and Elizabeth Plimack, MD, discuss clinical findings in the treatment of advanced RCC from the recent KCRS 2023 meeting, emphasizing the significance of circulating tumor cells, advances in imaging, and the potential of adjuvant therapies, particularly pembrolizumab. ....

Elizabeth Plimack , Robert Motzer , Evolving Treatments , Advanced Renal Cell Carcinoma , Renal Cell Carcinoma , Metastatic Renal Cell Cancer , Dose Reduction , Adjuvant Therapy , Toxicity Management , Blood Pressure , Thyroid Toxicity , Liver Toxicity , Hand Foot Syndrome ,

Managing Long-Term Toxicities of Combination Lenvatinib and Pembrolizumab in Advanced RCC

Drs Elizabeth Plimack and Robert Motzer discuss the long-term toxicities of combination lenvatinib/pembrolizumab in patients with advanced RCC, highlighting fatigue, GI discomfort, hand-foot syndrome, liver toxicity, thyroid toxicity, and proteinuria. ....

Elizabeth Plimack , Robert Motzer , Evolving Treatments , Advanced Renal Cell Carcinoma , Long Term Toxicities , Combination Lenvatinib , Renal Cell Carcinoma , Metastatic Renal Cell Cancer , Dose Reduction , Adjuvant Therapy , Toxicity Management , Blood Pressure , Thyroid Toxicity , Liver Toxicity , Hand Foot Syndrome ,

Lenvatinib Plus Pembrolizumab for Firstline Treatment of Advanced RCC

Elizabeth Plimack, MD, and Robert Motzer, MD, explain their preferences between TKI-IO combination therapies for patients with advanced RCC considering efficacy, side effects, and specific patient factors. ....

Elizabeth Plimack , Robert Motzer , Evolving Treatments , Advanced Renal Cell Carcinoma , Plus Pembrolizumab , Firstline Treatment , Renal Cell Carcinoma , Metastatic Renal Cell Cancer , Dose Reduction , Adjuvant Therapy , Toxicity Management , Blood Pressure , Thyroid Toxicity , Liver Toxicity , Hand Foot Syndrome ,

New Data Bring Excitement, Raise Questions in Advanced RCC

Although renal cell carcinoma remains a difficult-to-treat disease, with patients with clear cell histology experiencing a median overall survival of approximately 13 months and a 5-year overall survival rate of less than 10%, updated results from clinical trials examining emerging therapeutic strategies have spurred optimism. ....

United States , Eric Jonasch , Elizabeth Plimack , Briani Rini , Onclive Peer Exchange , American Society Of Clinical Oncology Annual Meeting , Clinical Oncology Annual Meeting , Frontline Advanced , Statpearls Publishing , Genitourinary Cancers , Gu Cancer ,