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Researchers explore cost-effective Identification method for novel SARS-CoV-2 variants


Researchers explore cost-effective Identification method for novel SARS-CoV-2 variants
Several novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern have emerged since the inception of the pandemic. These variants often displaying enhanced infectiousness and virulence compared with wild-type strain. Whole genome sequencing is currently the gold standard in the identification and monitoring of these lineages. However, the set-up costs and operational requirements of facilities capable of processing such large sample volumes have been prohibitive, exceeding what is clinically actionable for most patients.
In a new study, recently released on the preprint server
medRxiv , a rapid and cost-effective method of detecting known variants of concern has been developed utilizing capillary electrophoresis, allowing local facilities to screen for and track SARS-CoV-2 variants of concern and implement reactionary procedures. ....

United States , United Kingdom , Michael Greenwood , Multiplex Fragment Analysis Identifies , Image Credit , North Texas , Coronavirus Disease Covid 19 , Ars Cov 2 , Ucleic Acid , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein , Whole Genome Sequencing , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , மைக்கேல் கிரீன்வுட் , படம் கடன் , வடக்கு டெக்சாஸ் ,

Join a brief introduction to Nucleic Acid Gel Stains: exploring safer dyes and Non-UV imaging solutions


Join a brief introduction to Nucleic Acid Gel Stains: exploring safer dyes and Non-UV imaging solutions
At Pittcon, we are featuring our advanced Gel Box Illuminator that provides clear visualization of DNA after electrophoresis. It is optimized for use with both Red and Green dyes (no EtBr) and generates no UV radiation. For more information go to: Gel Box Illuminator
Image Credit: OMEC Medical
OMEC s innovative ODM and OEM capabilities leverage and optimize light and optics. We are a unique vendor in this field and offer specialized solutions to our partners who are seeking optics experts.
We are also developing an inexpensive, easy-to-use PCR, ideal for quick turnaround lab experiments and student lab education. ....

Gel Box Illuminator , Gel Box , Nucleic Acid Gel Stains , Nucleic Acid , கேள் பெட்டி வெளிச்சம் , கேள் பெட்டி ,

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation


Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation
Researchers have developed a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein – something which could inform future therapeutic research.
Advances in genomics, proteomics and mass spectrometry have enabled scientists to identify specific glycans on proteins and their association with diseases. However, these methods are expensive, require highly trained experts to perform and are not easily available.
Researchers Zhengliang L. Wu and James M. Ertelt released the N-glycans present on a glycoprotein and labeled them enzymatically using fluorophore-conjugated sialic acid and fucose, and separated them using gel electrophoresis. The fingerprint of the gly ....

Ramya Dwivedi , Coronavirus Disease Covid 19 , Sars Cov 2 , Spike Protein , Corona Virus , Gel Electrophoresis , Mass Spectrometry , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ரம்யா டுவிவேடி , ஸ்பைக் ப்ரோடீந் , கொரோனா வைரஸ் , நிறை ஸ்பெக்ட்ரோமெட்ரி , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,