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Pamrevlumab for Idiopathic Pulmonary Fibrosis

This randomized clinical trial compares the efficacy and safety of pamrevlumab vs placebo for patients with idiopathic pulmonary fibrosis. ....

United States , San Diego , Eteläuomen Läi , University Of California San Diego , South Korea , Roche Genentech , Eisai Pharma , Shionogi Pharma , Ganesh Raghu , Astellas Pharma , Taiho Pharma , Key Research , International Conference On Harmonisation , National Research Foundation Of Korea , Bristol Myers Squibb , Technology Of China , National Institutes Of Health , American Thoracic Society , University Of Washington , Korean National Institute Of Health , Institute Inc , Boehringer Ingelheim , Drug Administration , Group Information , National Nature Foundation Of China , Technology Institute ,

Acetaminophen for Prevention and Treatment of Organ Dysfunction

This randomized trial assesses whether acetaminophen would increase the number of days alive and free of organ support to day 28 among critically ill ....

United States , San Diego , Christopher Seymour , Biomerieux Biomarker , National Institutes Of Health , Kiniksa Pharmaceuticals , Gilead Pharmaceuticals , Protocol Committee , Blood Institute , Department Of Defense , Puretech Health , California Institute Of Regenerative Medicine , Quantum Health , Denver Health Medical Center , Vanderbilt University Medical Center , Institute Inc , Boehringer Ingelheim , Faron Pharmaceuticals , Blood Institute Prevention , Drug Administration , Group Information , National Heart , Sequential Organ Failure Assessment , Oxidative Stress , Early Treatment , Acute Lung Injury ,

Methylprednisolone as Adjunct to Endovascular Thrombectomy for Large-Vessel Occlusion Stroke

This clinical trial assesses the efficacy and adverse events of adjunctive intravenous low-dose methylprednisolone to endovascular thrombectomy for patients wit ....

Mei Yang , Min Zhang , De Yang , United States , Qian Xi , Chang Liu , United Kingdom , Lin Jiang , Eteläuomen Läi , Los Angeles , Nei Mongol , Xiang Liu , Zhouzhou Peng , Youlin Wu , Qingwu Yang , Guoyong Zeng , Shiwei Luo , Jinfu Ma , Jian Wang , Jun Luo , Jie Yang , Tieying Cai , Bo Li , Daoyou Cheng , Thanhn Nguyen , Jiandi Huang ,

Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial | Infectious Diseases | JAMA

This randomized clinical trial compares the efficacy and safety of letermovir vs valganciclovir prophylaxis for cytomegalovirus (CMV) disease in CMV-seronegativ ....

United States , University Of Washington , San Diego , Ajitp Limaye , Merck Co Inc , Merck Co , European Medicines Agency , American Society Of Nephrology Kidney Week , Gilead Sciences , Merck Sharp Dohme , American Transplant Congress , Drug Administration , Good Clinical Practice , International Conference , Harmonization Guideline , Secondary Efficacy Outcomes , Efficacy Outcomes , Size Calculation , Efficacy Outcome , Interest Disclosures , Viiv Healthcare , Drs Strizki , Merck Sharp , Infectious Disease Week , American Society , Nephrology Kidney Week ,

Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial | Cerebrovascular Disease | JAMA

This randomized clinical trial assesses the effect of intra-arterial alteplase infusion vs placebo on functional outcomes (modified Rankin Scale scores) among p ....

Eteläuomen Läi , United States , New Orleans , Comunidad Autonoma De Cataluna , Cooperativa Invictus , Spanish Ministry Of Health , National Institutes Of Health Stroke Scale , Group Information , Boehringer Ingelheim , Department Of Neuroscience , International Conference On Harmonization , Alberta Stroke Program Early Ct Score , Centre Esther Koplowitz , International Stroke Conference , Centre De Recerca Biom , Programme Generalitat De Catalunya , Institute Inc , Rankin Scale , Cerebral Ischemia , Chemical Optimization , Cerebral Embolectomy , International Conference , Study Sites , Central America , Alberta Stroke Program Early , National Institutes ,