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Pamrevlumab for Idiopathic Pulmonary Fibrosis

This randomized clinical trial compares the efficacy and safety of pamrevlumab vs placebo for patients with idiopathic pulmonary fibrosis.

United statesSan diegoEteläuomen läiUniversity of california san diegoSouth koreaRoche genentechEisai pharmaShionogi pharmaGanesh raghuAstellas pharmaTaiho pharmaKey researchInternational conference on harmonisationNational research foundation of koreaBristol myers squibbTechnology of china

Acetaminophen for Prevention and Treatment of Organ Dysfunction

This randomized trial assesses whether acetaminophen would increase the number of days alive and free of organ support to day 28 among critically ill

United statesSan diegoChristopher seymourBiomerieux biomarkerNational institutes of healthKiniksa pharmaceuticalsGilead pharmaceuticalsProtocol committeeBlood instituteDepartment of defensePuretech healthCalifornia institute of regenerative medicineQuantum healthDenver health medical centerVanderbilt university medical centerInstitute inc

Methylprednisolone as Adjunct to Endovascular Thrombectomy for Large-Vessel Occlusion Stroke

This clinical trial assesses the efficacy and adverse events of adjunctive intravenous low-dose methylprednisolone to endovascular thrombectomy for patients wit

Mei yangMin zhangDe yangUnited statesQian xiChang liuUnited kingdomLin jiangEteläuomen läiLos angelesNei mongolXiang liuZhouzhou pengYoulin wuQingwu yangGuoyong zeng

Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial | Infectious Diseases | JAMA

This randomized clinical trial compares the efficacy and safety of letermovir vs valganciclovir prophylaxis for cytomegalovirus (CMV) disease in CMV-seronegativ

United statesUniversity of washingtonSan diegoAjitp limayeMerck co incMerck coEuropean medicines agencyAmerican society of nephrology kidney weekGilead sciencesMerck sharp dohmeAmerican transplant congressDrug administrationGood clinical practiceInternational conferenceHarmonization guidelineSecondary efficacy outcomes

Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial | Cerebrovascular Disease | JAMA

This randomized clinical trial assesses the effect of intra-arterial alteplase infusion vs placebo on functional outcomes (modified Rankin Scale scores) among p

Eteläuomen läiUnited statesNew orleansComunidad autonoma de catalunaCooperativa invictusSpanish ministry of healthNational institutes of health stroke scaleGroup informationBoehringer ingelheimDepartment of neuroscienceInternational conference on harmonizationAlberta stroke program early ct scoreCentre esther koplowitzInternational stroke conferenceCentre de recerca biomProgramme generalitat de catalunya

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