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Computer simulation model identifies key factors for successful transit of sperm in the genital tract


Computer simulation model identifies key factors for successful transit of sperm in the genital tract
A research team at the Humboldt University Berlin and the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) developed an agent-based computer model to simulate the journey of sperm cells through the female genital tract. Key factors for a successful transit could be identified without the use of animal experiments and were published in the scientific journal PLoS Computational Biology .
During mating in wildlife species, males transfer millions of sperm into the female genital tract. On the way to the egg cell the sperm have to pass through the genital tract. Very few of the sperm cells actually succeed in passing through and reaching the vicinity of the egg cell. Those that do will then be conditioned for fertilisation. Mechanisms underlying sperm selection and, therefore, reproductive success are largely unknown, as their experimental study in the living org ....

Jorin Diemer , Edda Klipp , Emily Henderson , Leibniz Institute For Zoo , Humboldt University Berlin , Theoretical Biophysics Department , Wildlife Research , Leibniz Institute , Doctoral Student , Theoretical Biophysics , எமிலி ஹென்டர்சன் , ஹம்போல்ட் பல்கலைக்கழகம் பெர்லின் , வனவிலங்கு ஆராய்ச்சி , முனைவர் மாணவர் , கோட்பாட்டு உயிர் இயற்பியல் ,