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Streptokinase Helps to Manage Acute Pancreatitis by Angela Mohan on June 28, 2021 at 10:21 AM Streptokinase plays a vital role in the management of severe acute pancreatitis, as per the new study. Detailing about the study, Rajesh Gupta, Professor and Head, Department of Surgical Gastroenterology, said, Streptokinase has been used since early 1960 s for dissolution of intra-vascular thrombosis in pulmonary thromboembolism, myocardial infarction and deep vein thrombosis. The Department of Surgical Gastroenterology in close collaboration with the Department of Medical Gastroenterology started off-label use of streptokinase in 2013. The idea to use streptokinase in patients of severe acute pancreatitis was conceptualised after we observed its successful use in chest collections by pulmonologists. ....