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Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

New York , United States , United Kingdom , Mcgowan Jr , Biofire Filmarray , J Clin Microbiol , Ann Clin Microbiol Antimicrob , Fischer Elsevier , European Society Of Intensive Care Medicine , Society For Healthcare Epidemiology Of America , European Respiratory Society , Pbritish Thoracic Society , European Society Of Clinical Microbiology , Infectious Diseases Society Of America , American Thoracic Society , Global Burden , Disease Study , Infectious Diseases Society , American Thoracic , Infect Dis , European Society , Intensive Care Medicine , Clinical Microbiology , Infectious Diseases , Microbiol Infect , Englj Med ,

Citizen Science for Skin Microbiome Research—A 'Microbiome-friendly' Case Study

To assess the potential of citizen science for skin microbiome research, the work described here used a consumer test kit deployed in a pilot study of 59 participants to collect data. The results of a case study and more are outlined. ....

United States , United Kingdom , Clin Pharmacol , J Womens Dermatol , Jddgj Dtsch Dermatol , Public Health , Project Acari , Northwestern United States , American Gut Project , Bras Dermatol , Rev Clin Pharmacol , Drug Resist , Clin Cosmet Investig Dermatol , Dermatol Sci , Exp Dermatol , Oral Doxycycline , Clin Aesthetic Dermatol , Dermatol Res , Dtsch Dermatol Ges , Cosmet Investig Dermatol , Contact Atopic Occup Drug , Med Bull , British Gut , Genet Med , Citizen Science ,

Utilizing stem cells to support and aid cancer therapy

In this article, Sino Biological discusses how stem cells can be used to support and aid cancer therapy and treatment. They discuss different types of stem cells, pathways to target and how to best produce them. ....

Multimechanistic Oncolytic , Alex Smith , International Journal Of Biochemistry Cell Biology , Nature Communications , Sino Biological Inc Apr , Sino Biological Inc , Journal Of The National Cancer Institute , Pharmacological Research , Cancer Cell International , Sponsored Content , Cancer Stem Cells , Image Credit , Sino Biological , Interferon Gamma , Purity Determined , Reviews Cancer , Drug Resist , Stem Cell Therapy , Cancer Treatment , Molecular Mechanisms , Molecular Biosciences , New England Journal , Cellular Biochemistry , International Journal , Controlled Release , Control Release ,

Frontiers | Complication and Sequelae of COVID-19: What Should We Pay Attention to in the Post-Epidemic Era

Frontiers | Complication and Sequelae of COVID-19: What Should We Pay Attention to in the Post-Epidemic Era
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South Korea , United States , France General , United Kingdom , Inch On Gwangyoksi , Himachal Pradesh , Saudi Arabia , Drexel University , Reprod Genet , Nat Genet , Moreno Fern , Naborsc Sridhar , Dooghaie Moghadam , J Clin Endocrinol , Ann Clin Microbiol Antimicrob , Andrologiae Medicina , Ann Hepatol , Nephrol Carlton Vic , Freire Santana , Interdiscip Neurosurge , Razi Soofiyani , Abdul Lateef , Gandhih Guillain Barr , A Hong Kong , Al Zahrani , Gene In Human Airway Epithelial Cells ,

Regulatory mechanisms of lncRNAs in cancer glycolysis

163 are also involved in resistance to cisplatin, temozolomide and 5-fluorouracil via altering glycolysis in gastric cancer, glioblastoma and CRC, respectively. Interestingly, Fu et al reported that lncRNA plasmacytoma variant translocation 1 (PVT1) maintains Myc expression in Sjögren’s syndrome. This expression regulates proliferation and immune effects of CD4
+ T cells by controlling glycolytic metabolism.
164 Investigating the role of the PVT1-T cell glycolysis axis in tumor models may provide a novel insight for improving T cell-based immunotherapy.
The important role of lncRNAs-mediated glucose metabolic reprogramming in cancer adjuvant therapy, as discussed above, makes them promising targets for treating cancers. Several studies have revealed that siRNA, antisense oligonucleotides (ASOs) and clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) may be promising methods of targeting lncRNAs. ....

Gong Long , Hali Long , Cao Long , Chen Long , Asong Long , South Korea , Wum Lnc , Biochim Biophys Acta , Sonveauxp Monocarboxylate , Al Hasawi , El Amrani , Chemother Pharmacol , Chengdu University Of Traditional Chinese Medicine , Foundation Of Science , Technology Department Of Sichuan Province , Ethics Approval , Technology Department , Sichuan Province , Chengdu University , Traditional Chinese Medicine , Postdoctoral Science Foundation , Drug Resist , Mol Life , Exp Med , Cell Dev , Nat Rev ,