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Estimated mean probabilities of opioid dispensing following an emergency department (ED) encounter by patients with sickle cell disease or cancer with bone metastasis, conditional on exposure to no prescription drug monitoring program mandate, noncomprehensive, or comprehensive mandates, based on a difference-in-differences analysis including 18 345 ED encounters by 6239 patients with SCD and 26 427 ED encounters by 14 389 patients with cancer with bone metastasis in 2011-2017. Error bars depict 95% CIs. Figure 2. Morphine Milligram Equivalents of Opioids Dispensed Following an ED Encounter, by Prescription Drug Monitoring Program Mandates Estimated mean morphine milligram equivalents of opioids dispensed following an emergency department (ED) encounter by patients with sickle cell disease or cancer with bone metastasis, conditional on exposure to no prescription drug monitoring program mandate, noncomprehensive, or comprehensive mandates, based on a difference-in- ....