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Cancer-Prone Variants Tied to Poor Rhabdomyosarcoma Outcomes

Cancer-Prone Variants Tied to Poor Rhabdomyosarcoma Outcomes
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This breast cancer gene is less well known, but nearly as dangerous

This Breast Cancer Gene Is Less Well Known, but Nearly as Dangerous

ACMG Releases Two Important Secondary Findings Policies: Announces Recommendations for Future SF Reporting and New SF v3 0 List, with Plans to Update SF List Annually

Share this article Share this article BETHESDA, Md., May 20, 2021 /PRNewswire/ The American College of Medical Genetics and Genomics (ACMG) has just released an updated policy statement and gene list for the reporting of secondary findings (SF). Together, these two documents update the recommendations for SF reporting and unveil the highly anticipated recommended minimum gene list (SF v3.0) for reporting secondary findings in clinical exome and genome sequencing. The ACMG also declares its intent to update the SF gene list now annually, with a goal of publishing the updated list each January. Genetics in Medicine. Our group worked very hard on this update, taking a thoughtful and careful approach that balances the goals of keeping it as a minimum list while also providing results that will impact patients and their families in a positive way, said lead author and co-chair of the ACMG SFWG, David T. Miller, MD, PhD, FACMG.

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