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TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods

TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods
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Let s make poor reporting of early phase dose finding clinical trials a thing of the past

In 2017, I was drafting the first manuscript for a phase I clinical trial. I was familiar with the consolidated standards of reporting trials (Consort) for randomised parallel group trials, so I was surprised by the absence of Consort reporting guidance tailored for early phase dose finding trials. After searching top medical journals for published dose finding trials to assess how they had been reported, I found huge variation in what was being reported and their quality. This presented some big problems for medical research poor reporting in clinical trials jeopardises patient safety, erodes public trust, wastes vital resources, and hinders medical progress. Despite the pivotal role of these trials in shaping future clinical development, the importance of quality reporting had arguably been overlooked. It’s undeniable: we need robust reporting guidelines to enhance transparency and ensure reproducibility. Serendipitously, …

Does the virus exist? A critical need for resolution -- Health & Wellness -- Sott net

The airwaves of alt media are once again bristling with strings of activity over whether or not COVID-19 is a manipulated hoax that doesn't even involve an infectious microbial agent in the form of SARS-CoV-2. This one's not going away either -.

Scientists warn of majority of badly run medical

More than half of medical research clinical trials analysed showed a high risk of bias. It was especially bad for drug and alcohol studies.

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