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EMA Validates Type II Variation Application for Dostarlimab/Chemo for dMMR/MSI-H Primary Advanced or Recurrent Endometrial Cancer

The European Medicines Agency has validated a type II variation for potential approval of dostarlimab in combination with carboplatin and paclitaxel for the treatment of patients with mismatch repair–deficient/microsatellite instability–high primary advanced or recurrent endometrial cancer. ....

Hesham Abdullah , European Medicines Agency , Committee For Medicinal Products Human , Medicinal Products , Human Use , New England Journal , Medicines Agency , Endometrial Cancer , Msi H , Ruby Trial ,

Dostarlimab in Combination with Chemotherapy for the Treatment of Primary Advanced or Recurrent Endometrial Cancer: A Placebo-Controlled Randomized Phase 3 Trial (ENGOT-EN6-NSGO/GOG-3031/RUBY)

Mansoor R. Mirza, MD, reviews data from the phase 3 RUBY trial investigating dostarlimab in combination with carboplatin and paclitaxel for the treatment of primary advanced or recurrent endometrial cancer. ....

Mansoorr Mirza , Primary Advanced , Recurrent Endometrial Cancer , Placebo Controlled Randomized Phase , Endometrial Cancer , Advanced Endometrial Cancer , Primary Advanced Endometrial Cancer , Placebo Controlled , Engot En6 Nsgo , Gog 3031 , Ruby Trial , Ruby Study , Ruby Endometrial Cancer , Ruby Endometrial Carcinoma ,

GSK says RUBY dostarlimab phase 3 trial shows positive results

GSK PLC on Tuesday said interim results from the first part of its Ruby phase 3 clinical trial of its dostarlimab treatment in patients with primary advanced or recurrent endometrial cancer have shown. | March 28, 2023 ....

Harvey Dorset , Hesham Abdullah , Alliance News , Alliance News Ltd , All Rights , Gsk Plc Stock Exchange , Press Release , Ave Gsk Gb00bn7swp63 ,

Combining Immunotherapy With Chemo May Help Advanced Endometrial Cancer Patients Live Longer: Studies

The studies revealed that women in the later stages of endometrial cancer might have fewer chances of tumor return if they receive treatment that combines immunotherapy medicines along with ....

United States , Carol Aghajanian , Pamela Soliman , Md Anderson Cancer Center , American Cancer Society , Drug Administration , Society Of Gynecologic Oncology In Tampa , New England Journal , Gynecologic Oncology , Cancer Center , Endometrial Cancer ,

Dostarlimab Plus Chemotherapy Elicits PFS Benefit in Recurrent Endometrial Cancer

Dostarlimab plus standard-of-care chemotherapy generated a significant improvement in progression-free survival vs chemotherapy alone for patients with recurrent endometrial cancer, including those with mismatch repair–deficient, microsatellite instability–high tumors. ....

Copenhagen University Hospital , Department Of Oncology , Society Of Gynecological Oncology , Gynecological Oncology , Annual Meeting , Chief Oncologist , Ruby Trial , Sgo Annual Meeting , Endometrial Cancer ,