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Despite the discovery of protein arginine methyltransferase 5 more than 20 years ago, interest in the potential oncogene as a treatment target for patients with hematologic and solid malignancies has increased in recent years with the advancement of multiple novel agents through preclinical and early-phase studies.

United statesBiomed pharmacotherUlrikn lassenVarun mongaAmerican society of hematology annual meeting expositionUniversity of copenhagenAmerican society of clinical oncologyAmerican association for cancer research annual meetingDepartment of internal medicineDepartment of clinical medicineEuropean society for medical oncology congressUniversity of iowa carver college medicinePhase studiesDisplay mixedClinical trialsClinical oncology