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Anti-inflammatory effects of omega-3 fatty acids could help reduce depression


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The omega-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are found in oily fish. Researchers from the National Institute of Health Research (NIHR) Maudsley Biomedical Research Centre assessed the effects of high doses of EPA and DHA in lab-grown neurones and then in patients to help clarify how they reduce inflammation and depression. This novel approach allowed the scientists to identify an important molecular mechanism which can help inform the development of potential new treatments involving omega-3 fatty acids for patients with depression.
Lead author Dr Alessandra Borsini, NIHR Maudsley BRC Senior Postdoctoral Neuroscientist at King s College London, said: Using a combination of laboratory and patient research our study has provided exciting new insight into how omega-3 fatty acids bring about anti-inflammatory effects that improve depression. For some time we have known that omega-3 PUFA can induce anti-de ....

United Kingdom , City Of , Alessandra Borsini , Serena Rianjongdee , Anna Nicolaou , Franca Davenport , Carmine Pariante , King College London , National Institute Of Health Research , Senior Postdoctoral Neuroscientist At King College London , Academy Of Medical Sciences , China Medical University , University Of Manchester , National Institute For Health Research , Human Sciences , Department Of Health , Institute Of Psychiatry , Qs World University Rankings , Maudsley Biomedical Research Centre , National Institute , Health Research , Postdoctoral Neuroscientist , College London , Biomedical Research Centre , Biological Chemistry , Professor Carmine Pariante ,