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Coya Therapeutics to Present Proof-of-Concept Clinical Data for Low-Dose Interleukin-2 (ld IL-2) for the Treatment of Patients with Alzheimer's Disease (AD) at the 2023 Alzheimer's Association International Conference (AAIC)

The academic proof-of-concept open-label study evaluated the biological activity, cytokine and chemokine blood biomarkers, safety, and preliminary efficacy of low-dose interleukin-2 (ld IL-2) in 8 patients with mild-to-moderate AD. The study was conducted by Dr. Appel and Dr. Faridar at the Houston Methodist Hospital.

Coya’s investigational low-dose interleukin-2 (ld IL-2) for subcutaneous administration has been designed to enhance in vivo the anti-inflammatory function of regulatory T cells (Tregs).

Treg dysfunction has been associated with increased neuroinflammation, which is observed in AD and other neurodegenerative diseases, and may contribute to disease severity and progression. ....

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Lithium: Past, Present, and Future

Lithium: Past, Present, and Future
psychiatrictimes.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from psychiatrictimes.com Daily Mail and Mail on Sunday newspapers.

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Alzheimer's cognitive decline slows significantly with donanemab

Alzheimer's cognitive decline slows significantly with donanemab
alzheimersnewstoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from alzheimersnewstoday.com Daily Mail and Mail on Sunday newspapers.

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Low-Dose Solanezumab May Help Slow Cognitive Decline in AD With Mild Dementia

Low-dose solanezumab may have a potentially clinically meaningful effect on slowing the progression of AD with mild dementia. ....

Eli Lilly , Mini Mental State Examination , Disease Assessment Scale , Clinical Dementia Rating Scale ,

Low-Dose Solanezumab May Help Slow Cognitive Decline in AD With Mild Dementia

Low-dose solanezumab may have a potentially clinically meaningful effect on slowing the progression of AD with mild dementia. ....

Eli Lilly , Mini Mental State Examination , Disease Assessment Scale , Clinical Dementia Rating Scale ,