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Type 1 Diabetes Onset Tied to Decreased Complement Protein Levels

These findings suggest complement protein levels may be an important biomarker for type 1 diabetes. ....

Diabetes Autoimmunity Study , Type 1 Diabetes , Complement Protein Levels , Islet Autoimmunity , Complement Pathway , Daisy Study ,

Call for Type 1 Diabetes Screening Gains Momentum

Call for Type 1 Diabetes Screening Gains Momentum
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United States , Kimberly Kimber Simmons , Marian Rewers , National Diabetes Month , International Society Of Pediatric , Barbara Davis Center , Helmsley Charitable , University Of Colorado School Medicine , Diabetes Research Foundation , International Society , Adolescent Diabetes , Colorado School Medicine , New England Journal , Diabetes Complications , Control Trial , Childhood Diabetes Prevention Symposiumon , Diabetes Autoimmunity Study , Director Marian Rewers , Autoimmunity Screening , Juvenile Diabetes Research Foundation ,

One-Time Islet Autoantibody Testing Can Predict T1D Development in Adolescents

Research showed that screening 10-year-old adolescents who are at high risk of type 1 diabetes (T1D) for islet autoantibodies could predict future development of T1D. ....

United States , Lancet Child Adolescent Health , Lancet Child , Diabetes Prediction , Diabetes Autoimmunity Study , Diabetes Evaluation , Type 1 Diabetes , Islet Autoantibody ,

Paving the way for evidence-based population screening for type 1 diabetes

Since the 1980s, we have been gaining knowledge about the pathogenesis of type 1 diabetes
and found that the measurement of diabetes-associated autoantibodies against insulin,
glutamic acid decarboxylase, insulinoma-associated protein 2, and zinc transporter
8 has a central role in recognition of early stages of the disease in asymptomatic
people. In the 1990s, large prospective studies were established in Finland (the Diabetes
Prediction and Prevention [DIPP] study1), Germany (the BABYDIAB study2), Sweden (Diabetes
Prediction in Skåne Study3), and the USA (the Diabetes Autoimmunity Study in the Young
[DAISY]4) that followed up children with a high genetic risk of developing type 1
diabetes from birth until diagnosis of clinical type 1 diabetes. ....

United States , Southern Ostrobothnia , Endocrine Society , Study Group , American Diabetes Association , Diabetes Prediction , Diabetes Autoimmunity Study , American Diabetes , Environmental Determinants , Diabetes Evaluation ,

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Antibodies produced against the commonly used antibiotic, gentamicin, appear to increase the risk of type 1 diabetes in children already genetically at risk, scientists say. ....

United States , Paul Tran , Sharad Purohit , Emily Henderson , Yale University , Nature Communications , College Of Georgia , National Institutes Of Health , World Health Organization , Medical College , Diabetes Autoimmunity Study , Diabetic Autoantibody , Genomics Industry Focus , Environmental Determinants , Allied Health Sciences , National Institutes , Type 1 Diabetes , Immune Response ,