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IL-23 inhibitors may have a lower risk of paradoxical eczema in comparison to other biologics

1. Interleukin-23 inhibitors had a lower risk of developing paradoxical eczema when treated for plaque psoriasis compared to TNF inhibitors, IL-17 inhibitors and IL-12/23 2. Clinical features associated with increased paradoxical eczema risks included increasing age, history of atopic dermatitis, and history of hay fever. The risk was also lower in males. Evidence Rating Level: ....

United Kingdom , British Association Of Dermatologists Biologics , Rating Level , British Association , Dermatologists Biologics , Immunomodulators Register , Atopic Dermatitis , Il 23 Inhibitor , Plaque Psoriasis ,

Interleukin-23 Inhibitors Linked to Lower Risk for Eczema in Patients With Psoriasis

Among patients with psoriasis treated with biologics, those receiving IL-23 inhibitors had the lowest risk of developing paradoxical eczema; women, older patients, and those with a history of atopic dermatitis or hay fever had an increased risk. ....

British Association Of Dermatologists Biologics , British Association , Dermatologists Biologics , Immunomodulators Register , South Asian ,

Paradoxical Eczema Risk Low With Biologic Psoriasis Tx

Ali Al-Janabi, MA, and associates found that 273 (1%) of approximately 25,000 drug exposures in 13,699 biologic-treated patients with psoriasis were associated with paradoxical eczema. ....

United Kingdom , Ali Al Janabi , Samsung Bioepis , British Association Of Dermatologists Biologics , University Of Manchester , Study Group , Research Council , British Association Of Dermatologists , University Of Manchester England , British Association , Dermatologists Biologics , Immunomodulators Register , Medical Research , Sandoz Hexal , Medical Research Council , Atopic Dermatitis , Atopic Eczema , Biologic Therapy , Seasonal Allergic Rhinitis , Hay Fever , Ebrile Response , Salary Negotiations , Allergic Rhinitis , Nt Specialty , Ead And Neck Surgery Ent Speciality , Practice Management ,

Interleukin-23 inhibitors exhibit lowest paradoxical eczema risk in psoriasis treatment

Interleukin-23 inhibitors exhibit lowest paradoxical eczema risk in psoriasis treatment
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Ali Al Janabi , Kristen Dowd , Bygabrielle Capaldo , University Of Manchester Faculty Biology Medicine , British Association Of Dermatologists Biologics , Manchester Faculty , Biology Medicine , British Association , Dermatologists Biologics ,

Study: IL-23 Inhibitors Associated With Lowest Risk of Paradoxical Eczema in Patients With Plaque Psoriasis

Biologics for plaque psoriasis has been associated with an atopic dermatitis phenotype, paradoxical eczema, but the risk factors are not well known. ....

British Association Of Dermatologists Biologics , British Association , Dermatologists Biologics ,