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Jubilant Therapeutics Inc.'s Selective, Orally Administered PAD4 Inhibitor Demonstrates Activity in Rheumatoid Arthritis Preclinical Models

/PRNewswire/ Jubilant Therapeutics Inc., a clinical stage biopharmaceutical company advancing small molecule precision therapeutics to address unmet medical. ....

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ASH to present honorific awards

ASH to present honorific awards
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New York , United States , Memorial Sloan Kettering Cancer Center , Whitehead Institute , Massachusetts Institute Of Technology , Dana Farber Cancer Institute , University Of Pennsylvania , Mayo Clinic In Rochester , Connie Westhoff , Elizabeta Nemeth , Stephenm Ansell , Denisa Wagner , Harvey Lodish , Deepika Darbari , Jonathan Licht , Henrym Stratton , Los Angeles , Kwaku Ohene Frempong , Anthony Goldstone , Margareta Shipp , E Donnall Thomas , Martins Tallman , Wallaceh Coulter , University Of California , Whitehead Institute For Biomedical Research , Harvard Medical School ,

The Immune System's Weirdest Weapon

The Immune System's Weirdest Weapon
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United States , Region Flamande , Rachel Kratofil , Ed Reschke Getty , Shuichi Takayama , Denisa Wagner , Anna Huttenlocher , Kim Martinod , Paul Kubes , University Of Toronto , University Of Wisconsin At Madison , University Of Calgary , University Of Utah , Con Yost , Georgia Tech , Nades Palaniyar , ஒன்றுபட்டது மாநிலங்களில் , பால் க்யூப்ஸ் , பல்கலைக்கழகம் ஆஃப் டொராண்டோ , பல்கலைக்கழகம் ஆஃப் விஸ்கான்சின் இல் மாடிசன் , பல்கலைக்கழகம் ஆஃப் கல்கரி , பல்கலைக்கழகம் ஆஃப் உட்டா , ஏமாற்றுபவன் யொஸ்ட் , ஜார்ஜியா தொழில்நுட்பம் ,

The Super-Soldier Cells Hiding in Your Pus

The Super-Soldier Cells Hiding in Your Pus
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Jubilant Therapeutics Announces Research Collaboration with Boston Children's Hospital, Harvard Medical School, to Evaluate PAD4 Inhibitors in Autoimmune/Inflammation Disease Models

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BEDMINSTER, N.J., Feb. 25, 2021 /PRNewswire/ Jubilant Therapeutics Inc., a biopharmaceutical company advancing small molecule modulators to address unmet medical needs in oncology and autoimmune diseases, today announced a collaboration with Boston Children s Hospital (https://wistar.org/) to evaluate peptidyl arginine deiminase 4 (PAD4) inhibitors under development by Jubilant Therapeutics to explore the modulation of neutrophil extracellular traps (NETosis) in preclinical models of neutrophil regulation and rheumatoid arthritis (RA).
PAD4 is an enzyme that converts arginine to citrulline in histones and is highly expressed in neutrophils. Histone citrullination has been implicated in the formation of NETs which is believed to contribute to pro-inflammation and disease progression in many autoimmune disorders including RA, fibrosis, lupus and ARDS. ....

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