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Study illuminates how pain neurons protect the gut from damage

Pain has been long recognized as one of evolution's most reliable tools to detect the presence of harm and signal that something is wrong -; an alert system that tells us to pause and pay attention to our bodies. ....

Ddaping Yang , Isaac Chiu , Emily Henderson , Chiu Lab , Harvard Medical School , Blavatnik Institute , Study Senior Investigator , Associate Professor , Genomics Industry Focus , Acute Pain , Medical School ,

Unexpected Protective Properties of Pain - Neuroscience News

Pain neurons engage in direct cross-talk with goblet cells, or mucus-containing cells within the gut. During states of inflammation, pain cells stimulate goblet cells to release more mucus. Findings suggest the nervous system plays a key role in gut barrier maintenance and triggers protective mechanisms during periods of inflammation. ....

Malin Johansson , Amanda Jacobson , Ddaping Yang , Joseph Sifakis , Praju Vikas Anekal , Nicole Lee , Samantha Choi , Michael Anderson , Bana Jabri , Alexandra Sontheimer Phelps , Deepika Sharma , Youlian Zhou , Ekaterina Pesheva , Dennis Kasper , Jun Huh , Dylan Neel , Jay Thiagarajah , Meng Wu , Isaac Chiu , Samantha Riesenfeld , Tiandi Yang , Kimberly Meerschaert , Rachel Rucker , Liwen Deng , Chiu Lab Harvard Medical School , National Institutes Of Health ,

Study finds unexpected protective properties of pain

Study finds unexpected protective properties of pain
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Ddaping Yang , Isaac Chiu , Chiu Lab , Harvard Medical School , Blavatnik Institute ,