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Study: A subset of patients with localized prostate cancer may benefit from immunotherapies


Study: A subset of patients with localized prostate cancer may benefit from immunotherapies
In recent years, cancer immunotherapy has been effective in treating patients with immunogenic, or so-called hot tumors with increased levels of inflammation and the presence of immune cells in and around the tumors. Prostate cancer, however, is considered a cold tumor, with few immune cells recognizing and infiltrating prostate malignancies. Accordingly, prostate cancer has been found to respond poorly to the class of immunotherapies known as immune checkpoint inhibitors.
In previous work, a team led by medical oncologists at Beth Israel Deaconess Medical Center (BIDMC) identified a subset of prostate cancers that exhibited characteristics more typical of hot cancers. Now, in a paper appearing in the journal ....

Davidj Einstein , Emily Henderson , Beth Israel Deaconess Medical Center , Harvard Medical School , Clinical Cancer Research , Steven Balk , Prostate Cancer , Clinical Trial , Immune System , Kidney Cancer , Medical School , Pd L1 , எமிலி ஹென்டர்சன் , பெத் இஸ்ரேல் டேப்ககோணேஸ் மருத்துவ மையம் , ஹார்வர்ட் மருத்துவ பள்ளி , மருத்துவ புற்றுநோய் ஆராய்ச்சி ,