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Secondary prevention of cardiovascular disease, including cholesterol targets: summary of updated NICE guidance

### What you need to know

While mortality from acute cardiovascular disease (CVD) has been falling in most developed countries, more people are now living with established CVD, including coronary heart disease, peripheral arterial disease, and stroke or transient ischaemic attack. These individuals remain at high risk of subsequent cardiovascular events and mortality. In the UK, the cost of treating a myocardial infarction is £1310 higher in the first year for someone with established CVD than for a first event.1 Secondary prevention interventions, such as lowering of low density lipoprotein cholesterol (LDL-C), mitigate this risk and improve outcomes.2

Statins, ezetimibe, bempedoic acid, and injectable therapies are approved as lipid lowering therapies in the UK. However, use of these agents is variable,3 with about one fifth of people with CVD in England receiving no lipid lowering therapy.4 This is partly because of the absence of nationally agreed LDL-C targets for p ....

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Officers justified in Josephine County shooting, D.A.'s office says - KOBI-TV NBC5 / KOTI-TV NBC2

Officers justified in Josephine County shooting, D.A.'s office says - KOBI-TV NBC5 / KOTI-TV NBC2
kobi5.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kobi5.com Daily Mail and Mail on Sunday newspapers.

Josephine County , United States , David Wonderling , Thomas Rockholt , Josephine County District Attorney Office , Oregon State Police , Lakeshore Drive , Kenneth Ward , Josephine County District Attorney ,

Officers justified in Selma shooting, prosecutors say - KOBI-TV NBC5 / KOTI-TV NBC2

Officers justified in Selma shooting, prosecutors say - KOBI-TV NBC5 / KOTI-TV NBC2
kobi5.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kobi5.com Daily Mail and Mail on Sunday newspapers.

Josephine County , United States , David Wonderling , Thomas Rockholt , Josephine County District Attorney Office , Oregon State Police , Lakeshore Drive , Kenneth Ward , Josephine County District Attorney ,

Selma man shot by law enforcement arraigned

A Josephine County man shot Sunday by sheriff’s deputies as they were attempting to investigate a double homicide was arraigned Wednesday in Josephine County Circuit Court.
Thomas Charles Rockholt, 44. ....

David Wonderling , Thomas Charles Rockholt , Josephine County Circuit Court , Pass Police Department , Josephine County , Josephine County Circuit , Charles Rockholt , Kenneth Ward , Illinois Valley , Josephine County District Attorney , Grants Pass Police ,

Selma resident arrested after officers find two dead men in his yard

Investigators believe the two dead men shot each other; the resident was shot after threatening to burn the deceased bodies. ....

Josephine County , United States , David Wonderling , Lisa Turner , Thomas Rockholt , Oregon State Police Troopers , Josephine County Circuit Court , Josephine County District Attorney Office , Chief Deputy District Attorney , Josephine County District Attorney , Josephine County Deputies , Kenneth Ward , Unlawful Use , Classb Felony , Josephine County ,