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Hong Kong-led study discovers simeprevir as potent treatment for COVID-19 - China News


2021-05-10 07:35:59 GMT2021-05-10 15:35:59(Beijing Time) Xinhua English
HONG KONG, May 10 (Xinhua) A Hong Kong-led global study showed that a hepatitis C virus drug simeprevir can strongly suppress the replication of SARS-CoV-2, the virus that causes COVID-19, according to a press release issued by the Chinese University of Hong Kong (CUHK) on Monday.
Since the beginning of 2020, researchers from the CUHK and the University of Hong Kong have collaborated with over 30 scientists from local and overseas laboratories to search for an effective drug molecule for the treatment of COVID-19.
Using a combination of biochemistry, cell biology and computational chemistry techniques, the team discovered simeprevir can simultaneously target two major viral proteins that are critical to viral replication. Simeprevir is by now the only antiviral drug that can target more than one SARS-CoV-2 protein. ....

Xinhuaa Hong Kong Led , David Shu Cheong Hui , Chinese University Of Hong Kong , University Of Hong Kong , School Of Public Health , Hong Kong Led , Chinese University , Hong Kong , Chi Wai Chan , Public Health , Shu Cheong Hui , டேவிட் ஷு சியோங் ஹுய் , சீன பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , பள்ளி ஆஃப் பொது ஆரோக்கியம் , ஹாங் காங் வழிநடத்தியது , சீன பல்கலைக்கழகம் , ஹாங் காங் , பொது ஆரோக்கியம் ,

Hong Kong-led study discovers simeprevir as potent treatment for Covid-19


HONG KONG, May 10 (Xinhua): A Hong Kong-led global study showed that a hepatitis C virus drug simeprevir can strongly suppress the replication of SARS-CoV-2, the virus that causes Covid-19, according to a press release issued by the Chinese University of Hong Kong (CUHK) on Monday.
Since the beginning of 2020, researchers from the CUHK and the University of Hong Kong have collaborated with over 30 scientists from local and overseas laboratories to search for an effective drug molecule for the treatment of Covid-19.
Using a combination of biochemistry, cell biology and computational chemistry techniques, the team discovered simeprevir can simultaneously target two major viral proteins that are critical to viral replication. Simeprevir is by now the only antiviral drug that can target more than one SARS-CoV-2 protein. ....

David Shu Cheong Hui , Chinese University Of Hong Kong , University Of Hong Kong , School Of Public Health , Hong Kong Led , Chinese University , Hong Kong , Chi Wai Chan , Public Health , Shu Cheong Hui , டேவிட் ஷு சியோங் ஹுய் , சீன பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , பள்ளி ஆஃப் பொது ஆரோக்கியம் , ஹாங் காங் வழிநடத்தியது , சீன பல்கலைக்கழகம் , ஹாங் காங் , பொது ஆரோக்கியம் ,

Gut Microbiota Reflects Disease Severity in COVID-19 Patients


Gut Microbiota Reflects Disease Severity in COVID-19 Patients
Compared with non-COVID-19 patients, those with COVID-19 showed a substantially changed gut microbiome, whether or not they received medication. 
Caption: Image: CC BY 2.0 Go-tea 郭天
Celiac.com 03/15/2021 - COVID-19 is mainly a respiratory illness, but there is mounting evidence to indicate that the gut and gut microbiota may play a role in the disease. A team of researchers recently set out to determine if the gut microbiome is linked to disease severity in patients with COVID-19, and whether variations in microbiome composition might resolve with the passing of the SARS-CoV-2 virus.
The research team included Yun Kit Yeoh, Tao Zuo; Grace Chung-Yan Lui; Fen Zhang; Qin Liu; Amy YL Li; Arthur CK Chung; Chun Pan Cheung; Eugene YK Tso; Kitty SC Fung; Veronica Chan; Lowell Ling; Gavin Joynt; David Shu-Cheong Hui; Kai Ming Chow; Susanna So Shan Ng; Timothy Chun-Man Li; Rita WY Ng; Terry CF Yip; Grace L ....

Gavin Joynt , Kai Ming Chow , Amy Yl Li , Veronica Chan , Timothy Chun , Chung Yan Lui , Chun Pan Cheung , David Shu Cheong Hui , Qin Liu , Chun Kwok Wong , Tao Zuo , Yun Kit Yeoh , Grace Chung Yan Lui , Fen Zhang , Lowell Ling , Grace Lai Hung Wong , Gut Microbiota , Immune Response , Covid 19 , கவின் மகிழ்ச்சி , கை மிங் சோவ் , ஆமி யல் லி , வெரோனிகா சான் , தீமோத்தேயு சுன் , சுங் யான் லு , சுன் பான் செயுங் ,