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Oral Microbiome Determined Risk of Future Lung Cancer in Never Smokers

Dec 16, 2020
Lower microbiota diversity and abundance of Lactobacillales increased the risk
The composition of the oral microbiome influenced future lung cancer risk among men and especially women who never smoked, suggested findings from a nested case-control study in two large cohorts from Shanghai.
Among almost 75,000 participants in the Shanghai Women’s Health Study and over 61,000 participants in the Shanghai Men’s Health Study, subjects with lower levels of microbiota diversity had an increased risk of lung cancer compared to those with higher levels of microbial diversity (
P=0.05 and
P=0.04, depending on the statistical method used), Dean Hosgood, MD, of the Albert Einstein College of Medicine in Bronx, New York, and colleagues reported in ....

New York , United States , Harvard University , Ppam Harrison , David Christiani , Shanghai Women Health Study , Shanghai Men Health Study , Albert Einstein College Of Medicine , Shanghai Women , Health Study , Shanghai Men , Dean Hosgood , Albert Einstein College , University Th Chan School , Public Health , Contributing Writer , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஹார்வர்ட் பல்கலைக்கழகம் , பாம் ஹாரிசன் , ஷாங்காய் பெண்கள் ஆரோக்கியம் படிப்பு , ஷாங்காய் ஆண்கள் ஆரோக்கியம் படிப்பு , ஆல்பர்ட் ஐன்ஸ்டீன் கல்லூரி ஆஃப் மருந்து , ஷாங்காய் பெண்கள் , ஆரோக்கியம் படிப்பு , ஷாங்காய் ஆண்கள் ,

Type and abundance of mouth bacteria linked to lung cancer risk in non-smokers

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The type and abundance of bacteria found in the mouth may be linked to lung cancer risk in non-smokers, finds the first study of its kind, published online in the journal
Thorax.
Fewer species and high numbers of particular types of bacteria seem to be linked to heightened risk, the findings indicate.
Around one in four cases of lung cancer occurs in non-smokers and known risk factors, such as second hand tobacco smoke, background radon exposure, air pollution, and family history of lung cancer don t fully explain these figures, say the researchers.
The type and volume of bacteria (microbiome), found in the mouth has been associated with a heightened risk of various cancers including those of the gullet, head and neck, and pancreas. ....

David Christiani , Shanghai Women Health Study , Harvard University , Shanghai Men Health Study , Shanghai Women , Health Study , Shanghai Men , ஷாங்காய் பெண்கள் ஆரோக்கியம் படிப்பு , ஹார்வர்ட் பல்கலைக்கழகம் , ஷாங்காய் ஆண்கள் ஆரோக்கியம் படிப்பு , ஷாங்காய் பெண்கள் , ஆரோக்கியம் படிப்பு , ஷாங்காய் ஆண்கள் ,