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DarwinHealth Publication Reports Step-by-Step Protocol for its Tumor Checkpoint-Based, Compound-to-Clinic (C2C) Cancer Drug Discovery Pipeline: Elucidates a Patient-to-Model-to-Patient (PMP) Roadmap for Precision- and Mechanism-Based Identification and Clinical Validation of Novel, Investigational and FDA-Approved Therapeutic Agents Targeting Tumor Regulatory Architecture

DarwinHealth Publication Reports Step-by-Step Protocol for its Tumor Checkpoint-Based, Compound-to-Clinic (C2C) Cancer Drug Discovery Pipeline: Elucidates a Patient-to-Model-to-Patient (PMP) Roadmap for Precision- and Mechanism-Based Identification and Clinical Validation of Novel, Investigational and FDA-Approved Therapeutic Agents Targeting Tumor Regulatory Architecture
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DarwinHealth Scientists Publish Foundational Research Identifying Regulatory Mechanisms Controlling Cancer Cell States and Drug Response

DarwinHealth Scientists Publish Foundational Research Identifying Regulatory Mechanisms Controlling Cancer Cell States and Drug Response
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NEW YORK, Jan. 11, 2021 /PRNewswire/ DarwinHealth, Inc., a New York-based biotechnology and cancer drug discovery company announces the January 11, 2021 online publication in
Cell of a landmark paper, A Modular Master Regulator Landscape Controls Cancer Transcriptional Identity,
1,2 in which scientists from Columbia University and DarwinHealth apply the VIPER (Virtual Inference of Protein activity by Enriched Regulon) analysis algorithm to identify recurrent regulatory networks tumor checkpoints operative across the pancancer subtype continuum.
This research paper, with lead author Dr. Evan Paull, from the Department of Systems Biology at Columbia University, in conjunction with DarwinHealth Co-Founder, Professor Andrea Califano and Chief Scientific Office ....

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DarwinHealth Scientists Publish Foundational Research Identifying [...] | Comunicati stampa CataniaOggi

12 gennaio 2021 07:40
Fonte: Adnkronos
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NEW YORK, Jan. 11, 2021 /PRNewswire/ DarwinHealth, Inc., a New York-based biotechnology and cancer drug discovery company announces the January 11, 2021 online publication in Cell of a landmark paper, A Modular Master Regulator Landscape Controls Cancer Transcriptional Identity, 1,2 in which scientists from Columbia University and DarwinHealth apply the VIPER (Virtual Inference of Protein activity by Enriched Regulon) analysis algorithm to identify recurrent regulatory networks tumor checkpoints operative across the pancancer subtype continuum.
This research paper, with lead author Dr. Evan Paull, from the Department of Systems Biology at Columbia University, in conjunction with DarwinHealth Co-Founder, Professor Andrea Califano and Chief Scientific Officer, Dr. Mariano Alvarez and other investigators, presents results and analyses, using a novel Multi-Omics Master-Regulator Analysis framework (MOMA) ....

New York , United States , Columbia University , Asuntos Economicosy Transformacion , Andrea Califano , Evan Paull , Mariano Alvarez , Salud Carlos , Darwinhealth Co , Department Of Systems Biology At Columbia University , Prnewswire Darwinhealth Inc , Us National Institutes Of Health , New York Based , Virtual Inference , Enriched Regulon , Systems Biology , Darwinhealth Co Founder , Professor Andrea Califano , Chief Scientific Officer , Multi Omics Master Regulator Analysis , Instituto De Salud Carlos , Ministerio De Asuntos Economicos , Transformacion Digital , Master Regulator , Master Regulators , Master Regulator Blocks ,