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Limited Evidence Found for Effective Multiple Sclerosis Care

Limited Evidence Found for Effective Multiple Sclerosis Care
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Thomas Kaiser , Daniela Preukschat , Head Of The Chronic Diseases Division , Institute For Quality , Efficiency In Health Care Iqwi , Iqwig Drug Assessment Department , Federal Joint Committee , Health Care , Director Thomas Kaiser , Chronic Diseases Division , Drug Assessment Department , Registry Act ,

Lack of direct comparisons prevents assessment of upadacitinib's benefit in Crohn's disease

Like several immunosuppressive biologics, the JAK inhibitor upadacitinib is also approved for the treatment of Crohn's disease. Commissioned by the Federal Joint Committee (G-BA), the Institute for Quality and Efficiency in Health Care (IQWiG) has now investigated in an early benefit assessment whether the drug offers an added benefit versus the appropriate comparator therapy to patients with moderate to severe active Crohn's disease who have had an inadequate response, lost response or are intolerant to conventional therapy or a biologic agent. ....

Megan Craig , Daniela Preukschat , Iqwig Drug Assessment Department , Institute For Quality , Efficiency In Health Care Iqwi , Federal Joint Committee , Health Care , Drug Assessment Department , Drug Assessment , Medicinal Products , Health Care , Inflammatory Bowel Disease , Jak Inhibitor ,