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HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear. ....

United States , National University Of Singapore , Singapore General , Daniel Tenen , Emily Henderson , Cancer Science Institute Of Singapore , University Of Tor Vergata , Institute Of Hematology , Harvard Medical School , Cancer Science Institute , National University , Tor Vergata , Blood Diseases Hospital , New England Journal , Professor Daniel Tenen , Prof Tenen , Blood Cancer , Bone Marrow , Liver Cancer ,

NUS researchers identify novel pathways responsible for liver cancer

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. It is one of leading causes of cancer-related deaths globally, with more than 700,000 new cases and 600,000 estimated HCC deaths each year. HCC occurs most often in peopl ....

Daniel Tenen , Yvonne Tay , Kwon Junsu , Cancer Science Institute Of Singapore , Cancer Science Institute , Professor Daniel Tenen , Assistant Professor Yvonne Tay , Science Advances , Asst Prof Tay , Prof Tay , Research Fellow ,