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COVID-19 Antibodies Reduces the Immune Response Resulting to More Prolonged Symptoms in Long Haulers

COVID-19 long haulers suffer more prolonged symptoms, but research points to answers that might explain why it happens. But in time, the pandemic will be fully understood. ....

William Murphy , Dan Longo , Niels Jerne , Research Reveals Mechanisms That Make Coronavirus Variants , Network Hypothesis , Mutations Highly , Long Covid 19 ,

Evidence conflicts over efficacy of monoclonal antibodies in severe COVID


The
New England Journal of Medicine yesterday published two studies on the effectiveness of the interleukin-6 receptor antagonists tocilizumab and sarilumab in severely ill adult COVID-19 patients, one finding a benefit to a combination of the two drugs and the other showing no benefit with tocilizumab alone.
Early treatment with combo may be key
The first study, led by researchers at Imperial College London as part of an ongoing international platform trial, involved randomly assigning 803 patients in 113 intensive care units (ICUs) in six countries to receive tocilizumab, sarilumab, or usual care from April (tocilizumab) and June (sarilumab) through November 2020.
Median number of organ support–free days was 10 in the group receiving tocilizumab (353 patients), 11 in the sarilumab group (48 patients), and 0 in the control group (402 patients). Both monoclonal antibodies showed effectiveness in improving 90-day survival, time to ICU and hospital release, and Wo ....

United States , City Of , United Kingdom , Lindsey Baden , Eric Rubin , Dan Longo , Harvard University , Imperial College London , World Health Organization , Baylor College Of Medicine , New England Journal , Baylor College , North America , ஒன்றுபட்டது மாநிலங்களில் , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , லிண்ட்சே கெட்டது , எரிக் ரூபின் , டான் லாங்கோ , ஹார்வர்ட் பல்கலைக்கழகம் , ஏகாதிபத்தியம் கல்லூரி லண்டன் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , பேலர் கல்லூரி ஆஃப் மருந்து , புதியது இங்கிலாந்து இதழ் , பேலர் கல்லூரி , வடக்கு அமெரிக்கா ,