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DEBIOPHARM LAUNCHES PHASE 1/2 COMBINATION TRIAL INVESTIGATING BRAIN-PENETRANT SELECTIVE WEE1 INHIBITOR FOR BRAIN CANCER PATIENTS

Glioblastomas (GBM) are among the most aggressive and lethal tumors of the central nervous system with a 5-year survival rate of only 6.8%. Debiopharm is combining its potent, brain penetrant WEE1 inhibitor Debio 0123 with standard of care (SOC) therapy. Debio 0123 hopes to hinder DNA damage repair (DDR) and reverse the poor prognosis for patients with GBM. This multicenter clinical trial launched in the US, Spain and Switzerland is following the preclinical GBM data presented at the annual American Association for Cancer Research 2023 meeting (AACR 2023: Abstract #6185) in Orlando, Florida. LAUSANNE, Switzerland, May 17, 2023 /PRNewswire/ Debiopharm (www.debiopharm.com), a privately-owned, Swiss-based biopharmaceutical company aiming to establish tomorrow's standards ofcare to cure cancer and infectious diseases, today announced the start of its open-label Phase 1/2 study evaluating Debio 0123, a brain-penetrant and highly selective WEE1 inhibitor, in combination with temozolomid ....

United States , Patrick Roth , Victor Rodriguez Freixinos , Jordi Rodon Ahnert , Md Anderson Cancer Center , American Association For Cancer Research , University Hospital Zrich , Head Of Communications , American Association , Cancer Research , Cancer Center , Associate Medical Direction , University Hospital , Damage Repair , Glioblastomas Gbm Are Among The Most Aggressive And Lethal Tumors Of Central Nervous System Witha 5 Year Survival Rate Only 6 8 Debiopharm Is Combining Its Potent , Rain Penetrant Wee1 Inhibitor Debio 0123 With Standard Of Care Soc Therapy Hopes To Hinder Dna Damage Repair Ddr And Reverse The Poor Prognosis For Patients Gbm This Multicenter Clinical Trial Launched In Us , Pain And Switzerland Is Following The Preclinical Gbm Data Presented At Annual American Association For Cancer Research 2023 Meeting Aacr Abstract 6185 In Orlando , Lorida Lausanne , May 17 , 023 Prnewswire Debiopharm Www Com , A Privately Owned , Wiss Based Biopharmaceutical Company Aiming To Establish Tomorrow 39s Standards Ofcare Cure Cancer And Infectious Diseases , Oday Announced The Start Of Its Open Label Phase 1 2 Study Evaluating Debio 0123 , A Brain Penetrant And Highly Selective Wee1 Inhibitor , N Combination With Temozolomide Tmz In Patients Recurrent Or Progressive Glioblastoma And Rt Soc Newly Diagnosed The Initial Phase Of This Study Aims To Define Recommended 2 Doses Debio 0123 Gbm Is Among Most Aggressive Common Lethal Tumors Central Nervous System Disease Representsa Major Cause Morbidity Mortality Affecting More Than 13 , 000 Americans And Causing The Death Of About 10 ,

Debiopharm International SA: DEBIOPHARM LAUNCHES PHASE 1/2 COMBINATION TRIAL INVESTIGATING BRAIN-PENETRANT SELECTIVE WEE1 INHIBITOR FOR BRAIN CANCER PATIENTS

Glioblastomas (GBM) are among the most aggressive and lethal tumors of the central nervous system with a 5-year survival rate of only 6.8%.Debiopharm is combining its potent, brain penetrant ....

United States , University Hospital , Patrick Roth , Jordi Rodon Ahnert , Gewinn Nur , Victor Rodriguez Freixinos , Prnewswire Debiopharm , Head Of Communications , American Association For Cancer Research , Md Anderson Cancer Center , National Brain Tumor Society , American Association , Cancer Research , Cancer Center , Associate Medical Direction , Damage Repair , Brain Tumor ,

SUPES PREVIEW: Navigation Center for Humboldt's Homeless, Civil Penalties for Weed Growers That Have Ignored Abatement Notices, $2.3 Million Loan Transfer for Samoa Peninsula Property, and More!

SUPES PREVIEW: Navigation Center for Humboldt's Homeless, Civil Penalties for Weed Growers That Have Ignored Abatement Notices, $2.3 Million Loan Transfer for Samoa Peninsula Property, and More!
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SUPES PREVIEW: How 'Bout a New Signal on Eureka's F Street? And the Humboldt Bay Trail to CR? PLUS: Opioid Lawsuit Settlement and More! | Lost Coast Outpost

SUPES PREVIEW: How 'Bout a New Signal on Eureka's F Street? And the Humboldt Bay Trail to CR? PLUS: Opioid Lawsuit Settlement and More! | Lost Coast Outpost
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SUPES PREVIEW: Several Offshore Wind-Related Actions Up For Consideration During this Week's Meeting | Lost Coast Outpost

SUPES PREVIEW: Several Offshore Wind-Related Actions Up For Consideration During this Week's Meeting | Lost Coast Outpost
lostcoastoutpost.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lostcoastoutpost.com Daily Mail and Mail on Sunday newspapers.

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