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FDA approves first systemic therapy for children with BRAF V600E-mutated low-grade glioma

The FDA approved dabrafenib with trametinib for children with previously untreated low-grade glioma who harbor BRAF V600E mutations and require systemic therapy.The approval — which applies to children aged 1 year or older — is the first for a systemic therapy for first-line treatment of this patient population. ....

United States , Rogerj Packer , Dabrafenib Tafinlar , Mindy Valcarcel , Trametinib Mekinist , Behavioral Medicine At Children National Hospital , Behavioral Medicine , National Hospital ,

Thyroid Carcinoma Treatment Regimens

Find information about available non-chemotherapy treatments for thyroid carcinoma, including total thyroidectomy, radiodine treatment, and ablation. ....

New York , United States , United Kingdom , Lake Forest , Pembrolizumab Keytruda , Vemurafenib Zelboraf , Larotrectinib Vitrakvi , Selpercatinib Retevmo , Trametinib Mekinist , Chemother Pharmacol , Fluorouracil Dacarbazine , J Clin Endocrinol , Entrectinib Rozlytrek , Vandetinib Caprelsa , Tumeursa Calcitonine , Sunitinib Sutent , Dabrafenib Tafinlar , Pazopanib Votrient , Axitinib Inlyta , Levantinib Lenvima , Dabrafenib Trametinib , Fresenius Kabi , Cabozantinib Cabometyx , Everolimus Afinitor , Fluorouracil Streptozocin , Sorafenib Nexavar ,