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MediGene AG (via Public) / Identification of ten novel tumor-specific antigens immunogenic for T cells

Identification of ten novel tumor-specific antigens immunogenic for T cells Planegg/Martinsried and Montréal - 10 April 2021. Medigene AG (Medigene, FSE: MDG1, Prime Standard), a clinical stage immuno-oncology company focusing on the development of T cell immunotherapies, today presents the screening and identification of novel immunogenic tumor-specific antigens (TSAs) derived from non-coding regions of the human genome at the American Association for Cancer Research Virtual Annual Meeting (AACR) 2021. The poster can be found on Medigene s website: https://www.medigene.com/technologies/abstracts Significant efforts are being dedicated worldwide to identifying novel TSAs as targets for cancer immunotherapy. In this respect, not only known proteins but also non-coding genetic regions of cells are studied as sources of peptides that can be presented by HLA molecules at the surface of tumor cells and be recognized by T cell receptors (TCRs). Such TSAs can provide new targets that all

Medigene AG: Focus on solid tumors - Discontinuation of MDG1021 development program

Medigene AG: Focus on solid tumors - Discontinuation of MDG1021 development program Conference call today, 3.00 pm CET (9.00 am ET) Planegg/Martinsried (pta025/28.01.2021/14:10) - 28 January 2021. The Executive Management of Medigene AG (Medigene, FSE: MDG1, Prime Standard), a clinical stage immuno-oncology company focusing on the development of T cell immunotherapies, with approval of the Supervisory Board decided today that, consistent with the company s recent decision to focus its development efforts on solid tumors, the MDG1021 development program is to be discontinued. Recruitment for the Phase I clinical trial of the T cell receptor-modified T cell (TCR-T) therapy MDG1021 directed against the antigen HA-1 in patients suffering from relapsed or persistent blood cancers after allogeneic (non-self) hematopoietic stem cell transplantation, which was initiated at the Leiden University Medical Centre (LUMC) in the Netherlands in mid-2020, will be put on hold with immediate effect

Medigene AG: Medigene erweitert den Patentschutz für ihre Technologien in Schlüsselmärkten wie den USA und Europa

Medigene AG: Medigene erweitert den Patentschutz für ihre Technologien in Schlüsselmärkten wie den USA und Europa
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Börse Express - Medigene AG: Medigene erweitert den Patentschutz für ihre Technologien in Schlüsselmärkten wie den USA und Europa

Börse Express - Medigene AG: Medigene erweitert den Patentschutz für ihre Technologien in Schlüsselmärkten wie den USA und Europa
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