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Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T) – is repeated multiple times in tandem. An example might be: CAG CAG CAG, in which the pattern CAG is repeated three times. ....

Ryan Yuen , Jin Szatkiewicz , Emily Henderson , University Of Toronto , School Of Medicine , Molecular Psychiatry , Genomics Industry Focus , Sick Children , Machine Learning ,

Novel age predictor helps investigate heterogeneity in brain aging

A new research paper was published in Aging (abbreviated as "Aging (Albany NY)" by Medline/PubMed and as "Aging-US" by Web of Science) on the cover of Volume 14, Issue 14, entitled, "Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease." ....

Yale University , United States , Davida Bennett , Christopher Gaiteri , Medline Pubmed , Morgane Levine , Steve Horvath , Albertt Higgins Chen , Emily Henderson , University Of California Los Angeles , Rush University Medical Center , California Los Angeles , Healthcare System , Altos Labs , Religious Orders Study , Rush Memory , Aging Project , Lzheimer 39s Disease ,