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Long-Term Follow-Up from CheckMate 214 in Advanced RCC

The expert panel discusses the 8-year follow-up data from CheckMate 214 looking at nivolumab plus ipilimumab in first-line advanced RCC and provide clinical insights on treatment decisions.

Advanced-renal-cell-carcinoma
Term-follow-up
Renal-cell-carcinoma
Nrcc
Advanced-rcc
Checkmate-214
Nivolumab
Ipilimumab
Metastatic-clear-cell-rcc
Ctla4-inhibition
Ctla4

Nivolumab/Ipilimumab vs Nivolumab Alone in Advanced Cancers Other Than Melanoma

1. Pooled overall survival and progression-free survival HR were found to be 0.95 and 0.88 for nivolumab/ipilimumab vs. nivolumab. 2. Pooled OR for grade 3-4 adverse events was found to be 1.84 for the combination compared to monotherapy Evidence Rating Level: 1 (Excellent) Study Rundown: Nivolumab/ipilimumab combination therapy has demonstrated improved progression-free survival (PFS) and

Information-services
Cochrane-library
Rating-level
Five-year-survival
Combined-nivolumab
Combination-imunotherapy
Ctla4
Pd-1-inhibitors
Chronic-disease
Oncology

Development Challenges in Microsatellite Stable mCRC

Dr Marshall discusses challenges associated with microsatellite stable metastatic colorectal cancer.

Johnl-marshall
Pd1
Ctla4
Immunotherapies
Immune-therapy-responses
Cold-tumors
Hot-tumors
Microbiome

Botensilimab and Balstilimab in Refractory Microsatellite Stable (MSS) mCRC

An overview of data presented at ESMO GI 2023 on combined botensilimab and balstilimab therapy in heavily pretreated patients with microsatellite stable metastatic colorectal cancer.

Johnl-marshall
Twitter
Colorectal-cancer
Cold-tumors
Microsatellite-stable-cancer
Botensilimab
Balstilimab
Ctla-4
Ctla4
Pd1
Tumor-mutational-burden

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