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Long-Term Follow-Up from CheckMate 214 in Advanced RCC

The expert panel discusses the 8-year follow-up data from CheckMate 214 looking at nivolumab plus ipilimumab in first-line advanced RCC and provide clinical insights on treatment decisions. ....

Advanced Renal Cell Carcinoma , Term Follow Up , Renal Cell Carcinoma , Advanced Rcc , Checkmate 214 , Metastatic Clear Cell Rcc , Ctla4 Inhibition , Metastatic Clear Cell Renal Carcinoma ,

The Role of CTLA-4 Inhibitors in NSCLC

Experts on non–small cell lung cancer discuss the role of CTLA-4 inhibitors in the NSCLC treatment landscape. ....

Evolving Treatment Paradigm , Advanced Non , Small Cell Lung Cancer , Non Small Cell Lung Cancer , Advanced Non Small Cell Lung Cancer , Advanced Nsclc , Non Small Cell Lung Cancer Treatment , Nsclc Treatment , Pd L1 ,

Nivolumab/Ipilimumab vs Nivolumab Alone in Advanced Cancers Other Than Melanoma

1. Pooled overall survival and progression-free survival HR were found to be 0.95 and 0.88 for nivolumab/ipilimumab vs. nivolumab. 2. Pooled OR for grade 3-4 adverse events was found to be 1.84 for the combination compared to monotherapy Evidence Rating Level: 1 (Excellent) Study Rundown: Nivolumab/ipilimumab combination therapy has demonstrated improved progression-free survival (PFS) and ....

Information Services , Cochrane Library , Rating Level , Five Year Survival , Combined Nivolumab , Combination Imunotherapy , Pd 1 Inhibitors , Chronic Disease ,

Development Challenges in Microsatellite Stable mCRC

Dr Marshall discusses challenges associated with microsatellite stable metastatic colorectal cancer. ....

Johnl Marshall , Immune Therapy Responses , Cold Tumors , Hot Tumors ,

Botensilimab and Balstilimab in Refractory Microsatellite Stable (MSS) mCRC

An overview of data presented at ESMO GI 2023 on combined botensilimab and balstilimab therapy in heavily pretreated patients with microsatellite stable metastatic colorectal cancer. ....

Johnl Marshall , Colorectal Cancer , Cold Tumors , Microsatellite Stable Cancer , Ctla 4 , Tumor Mutational Burden , Immune Checkpoint System ,