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Discovery of novel enzyme family holds potential for antibiotic development

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls. ....

Felipe Cava , Alice Wallenberg Foundation , Nature Communications , Hypoxic Research Facility , Swedish Research Council , Professor Felipe Cava , Infection Biology , Hypoxic Research , Professor Cava , Amino Acid , Cell Wall , Cross Linking , Infectious Diseases ,

Nanoengineered bioink improves tumor model accuracy

Scientists from the Terasaki Institute for Biomedical Innovation have developed a nanoengineered bioink with improved bonding and cross-linking capabilities for 3D bioprinting of tumor models. ....

Ali Khademhosseini , Lily Ramsey , Terasaki Institute For Biomedical Innovation , Terasaki Institute , Biomedical Innovation , Cross Linking , Ene Expression , N Vitro , Pancreatic Cancer ,

"Intermolecular Cross-Linking Reinforces Polymer Binders for Durable Al" by Qian Yao, Yansong Zhu et al.

Sodium-ion batteries show promising potential for large-scale energy storage. However, the large size and heavy mass of Na+ always results in huge volume change and inferior electrochemical stability, especially in alloy-type anode materials. Here, molecular engineering of the polymer binders, i.e., cross-linking of poly(acrylic acid) with glycerin (PAA-GLY), reinforces the mechanical properties, eliminates the active protons of PAA, and benefits electrolyte diffusion, thereby remarkably improving electrochemical performance. Using µ-Sn as an example, the cycle life at 2 A g−1 is extended from ≈26 cycles of PAA to ≈2000 cycles of PAA-GLY. Meanwhile, the initial Coulombic efficiency is promoted to 90.3%, allowing the fabrication step of electrode presodiation for full cells to be eliminated. Thus, the full cells run 300 cycles at 2 A g−1. In addition, the binder allows the thick electrode to exhibit an areal capacity of 6.8 mAh cm−2. This binder is also applied for µ-Bi and ....

Alloy Type Anodes , Cross Linking , Initial Coulombic Efficiency , Icrosized Particles ,