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Abbreviation: HC, healthy control. Figure 4 Effects of IL-27 (p28) on IL-8, IFN-α2 and IFN-ß in 4 different patients. Serum samples were used for cytokine measurements by Bio-Plex multiplex assay. The data analysis was performed in duplicate for each patient sample, and data are presented as the mean (SEM). Comparison of the different cytokine levels was performed using one-way ANOVA. A P-value of ....