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Interrupting treatment of vulnerable people on immune-suppressing medicines doubles their antibody response to Covid booster

Interrupting treatment of vulnerable people on immune-suppressing medicines doubles their antibody response to Covid booster
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United Kingdom , Joseph Gibbons , Queen Mary , Corinna Pade , Andy Ustianowski , National Institute For Health , National Infection Specialty , Care Research , Research Council , Vaccine Research Programme , Vaccine Response On Off Methotrexate , National Institute , Medical Research , Lancet Respiratory , Viral Pathology , Blizard Institute , Research Programme , Joint National Infection Specialty Lead ,

SMD - Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose


COVID-19 vaccine
In those who have not previously been infected and have so far only received one dose of vaccine the immune response to variants of concern may be insufficient.
The findings, published today in the journal
Science and led by researchers at Queen Mary University of London, Imperial College London and University College London, looked at immune responses in UK healthcare workers at Barts and Royal Free hospitals following their first dose of the Pfizer/BioNTech vaccine.
They found that people who had previously had mild or asymptomatic infection had significantly enhanced protection against the Kent and South Africa variants, after a single dose of the mRNA vaccine. In those without prior COVID-19, the immune response was less strong after a first dose, potentially leaving them at risk from variants.  ....

South Africa , United Kingdom , City Of , Joseph Gibbons , Rosemary Boyton , Corinna Pade , University College London , University Of Nottingham , Medicine At Imperial College London , Imperial College London , Queen Mary University Of London , Public Health England , Barts Health , Barts Charity , Research Council , Research Scientist At Queen Mary Blizard Institute , Queen Mary University , Royal Free , Viral Pathology , Queen Mary , Blizard Institute , Respiratory Medicine , Research Scientist , Postdoctoral Research Scientist , Royal Free Hospital , Rosetrees Trust ,

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose


Queen Mary University of London
In those who have not previously been infected and have so far only received one dose of vaccine the immune response to variants of concern may be insufficient.
The findings, published today in the journal Science and led by researchers at Queen Mary University of London, Imperial College London and University College London, looked at immune responses in UK healthcare workers at Barts and Royal Free hospitals following their first dose of the Pfizer/BioNTech vaccine.
They found that people who had previously had mild or asymptomatic infection had significantly enhanced protection against the Kent and South Africa variants, after a single dose of the mRNA vaccine. In those without prior COVID-19, the immune response was less strong after a first dose, potentially leaving them at risk from variants. ....

South Africa , United Kingdom , City Of , Joseph Gibbons , Rosemary Boyton , Corinna Pade , University College London , University Of Nottingham , Medicine At Imperial College London , Imperial College London , Queen Mary University Of London , Public Health England , Barts Health , Barts Charity , Research Council , Research Scientist At Queen Mary Blizard Institute , Queen Mary University , Royal Free , Viral Pathology , Queen Mary , Blizard Institute , Respiratory Medicine , Research Scientist , Postdoctoral Research Scientist , Royal Free Hospital , Rosetrees Trust ,

Lasting immunity against COVID-19 found after mild or asymptomatic infection: Study


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A healthcare worker holds a bottle of the Pfizer/BioNtech COVID-19 vaccine at Notre Dame home care, as the coronavirus disease outbreak continues in Brussels, on December 28, 2020. Reuters
London, December 28
Scientists have found evidence of protective immunity against COVID-19 in people up to four months after mild or asymptomatic coronavirus infection, providing hope for the long-lasting efficacy of vaccines.
The researcher, including those from Queen Mary University of London analysed antibody and T cell responses in 136 healthcare workers in the UK, who had mild or asymptomatic COVID-19 infection dating back to March.
The study, published in the journal Science Immunology, found that 89 per cent of healthcare workers analysed carried neutralising antibodies 16-18 weeks after infection. ....

United Kingdom , City Of , Joseph Gibbons , Corinna Pade , University College London , Postdoctoral Research Scientist At Queen Mary , Postdoctoral Research Assistant At Queen Mary , Imperial College London , Queen Mary University Of London , Queen Mary University , Science Immunology , Postdoctoral Research Assistant , Queen Mary , Postdoctoral Research Scientist , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , ஜோசப் கிப்பன்கள் , கொரின்னா பேட் , பல்கலைக்கழகம் கல்லூரி லண்டன் , போஸ்ட்‌டாக்டொரல் ஆராய்ச்சி விஞ்ஞானி இல் ராணி மேரி , போஸ்ட்‌டாக்டொரல் ஆராய்ச்சி உதவியாளர் இல் ராணி மேரி , ஏகாதிபத்தியம் கல்லூரி லண்டன் , ராணி மேரி பல்கலைக்கழகம் ஆஃப் லண்டன் , ராணி மேரி பல்கலைக்கழகம் , அறிவியல் நோயெதிர்ப்பு , போஸ்ட்‌டாக்டொரல் ஆராய்ச்சி உதவியாளர் ,