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Six Advantages of Regulating the Endocannabinoid System The endocannabinoid system (ECS) has already been a ground-breaking discovery for biology and cannabinoid science. Researchers have found new receptors and neurotransmitters that can be stimulated or suppressed to help treat various chemical imbalances, which stop the body from reaching a state of homeostasis. How come the intricacies and importance of the ECS remained unknown until the late 20th century? Because without finding out more about the properties of the cannabis plant, it would not have been possible to locate the ECS. Dr. Raphael Mechoulam and his team spent decades looking for an endogenous compound which produced similar effects to tetrahydrocannabinol (THC), finally identifying anandamide in 1992, which was promptly labelled the ‘human THC.’ ....