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When Waddington meets Helmholtz: EPR-Net for constructing the potential landscapes of complex non-equilibrium systems

When Waddington meets Helmholtz: EPR-Net for constructing the potential landscapes of complex non-equilibrium systems
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United Kingdom , Yue Zhao , Wei Zhang , Tiejun Li , Conrad Hal Waddington , Freie Universit , Zuse Institute Berlin , National Science , Science China , Science China Press , Peking University , National Science Review ,

Understanding how cell becomes person – with maths

Understanding how cell becomes person – with maths
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United Kingdom , Conrad Hal Waddington , Cell Systems , Laureate Fellowship ,

Using Waddington's Landscape to Bioprocess Stem Cells

Developing stem cell-based biotherapies depends crucially on differentiation. At Osaka University in Japan, Masahiro Kino-oka, PhD, professor in the department of biotechnology and director in the research base for cell manufacturability, uses Waddington’s epigenetic landscape to control differentiation of induced pluripotent stem cells (iPSCs) and create homogenous cultures. Although Waddington’s idea is not new, Kino-oka envisions unique advances in iPSC bioprocessing by using this concept. ....

United Kingdom , Conrad Hal Waddington , Osaka University , Masahiro Kino Oka ,