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Vital Funding supports Investigation of PEG Variants

To prevent active biopharmaceuticals from being attacked by our immune systems a standard procedure used since the 1980’s has been to create a "cloak of invisibility" around the drug by means of conjugation with the polymer polyethylene glycol (PEG). Click to read more. ....

Holger Frey , Johannes Gutenberg University Mainz , European Research Council , Macromolecular Chemistry , Advanced Grant ,

Evaluating nano alum as a substitute for conventional alum-based vaccine adjuvant

Researchers evaluated the performance and safety of nano alum adjuvant as next-generation coronavirus disease 2019 (COVID-19) vaccine antigens. ....

Human Vaccines , Coronavirus Disease Covid 19 , Bottom Up , Covid 19 , Immune Response , N Vitro , N Vivo , Lymph Node ,

Enzymes with diverse functions can be rationally harnessed to offer traceless protein synthesis

A multi-enzyme platform is developed for sequence-unconstrained traceless protein synthesis and modification with either synthetic peptides or recombinant proteins, according to a new study out of Chinese Academy of Sciences and Fresenius Kabi. ....

Fresenius Kabi , Emily Henderson , Institute Of Microbiology , National Science , Chinese Academy Of Sciences , Chinese Academy , National Science Review , Protein Synthesis , Life Science ,

Transcripts for MSNBC The Rachel Maddow Show 20240604 04:27:00

Electoral politics as an objective way of deciding who has power and how questions get resolved in our country. the two parties are engaged right now in fundamentally different politics. one is around solving problems, and the other is an conjugation of an in micro, seat right? on earth one, there is serious stuff going on right now. a presidential assassination in a nearby troubled country that we are inextricably entwined with. ending a 20-year war, trying to save our allies there while we re on our way out the door. innovating new approaches to rapidly evolving covid challenge. and evading new approaches to long-standing intractable, deadly, only in america problems like mass gun violence. on earth one it s like dude, oh look, rudy giuliani just lost his license to practice law and d.c. too. as well as new york. because he is the president s personal lawyer and he s been doing lots of lying about whether the last republican ....

Earth One , Only In America Problems Like Mass Gun Violence , Covid Challenge , New York State , Rudy Giuliani ,

New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution


New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution
Several processes in the human body are regulated by biochemical reactions involving hydrogen peroxide (H
2O
2).
2O
2 is generally toxic because of its oxidant character. The latter means that it converts (oxidizes) biochemical molecules like proteins and DNA.
The oxidizing property of H
2O
2 is of potential therapeutic relevance for cancer, though: deliberately causing tumor cells to increase their H
2O
2 concentration would be a way to destroy them. In light of this, but also for monitoring pathologies associated with H
2O
2 overproduction, it is crucial to have a means to reliably quantify hydrogen peroxide concentrations in the extracellular environment. ....

Leonardo Puppulin , Emily Henderson , Nano Life Science Institute , Kanazawa University , Hydrogen Peroxide , Gold Nanoparticles , Raman Spectroscopy , எமிலி ஹென்டர்சன் , நானோ வாழ்க்கை அறிவியல் நிறுவனம் , கனசாவா பல்கலைக்கழகம் , ராமன் ஸ்பெக்ட்ரோஸ்கோபி ,