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The PAncreatic Surgery Composite Endpoint PACE – Development and Validation of a Clinically Relevant Endpoint Requiring Lower Sample Sizes

To provide a composite endpoint in pancreatic surgery.Single endpoints in prospective and randomized studies have become impractical due to their low frequency and the marginal benefit of new interventions.Data from prospective studies were used to develop (n=1273) and validate (n=544) a composite endpoint based on postoperative pancreatic fistula, post-pancreatectomy hemorrhage as well as reoperation and

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