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Thank you very much for that question. I absolutely believe, we as an organization believe it is an important incentive. It puts a spotlight on research and children. It they risks it at a certain level because there is an incentive and that becomes a very important issue as Companies Look across their portfolios and decide where to make investments to battlers la health of the nation. That in my mind is a big deal. How it could be made better, right now is it is provisional or temporary trial. It could be a stronger statement if it was permanent. We the people want to invest and make incentives and opportunities for research with children. While i have the money there is one of the eighth thing i would like to comment, particularly impressed with the comment about the voice of the patient. And i think as do many of my colleagues within shire and across the industry, though rare disease world, is hugely informative. Often times pa ....
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