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Adding Metabolism to Models of Bioprocessing

Adding Metabolism to Models of Bioprocessing
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Artificial Intelligence Employed to Improve Antibody Quality

Artificial Intelligence Employed to Improve Antibody Quality
Source: janiecbros/Getty Images
A group from Imperial College London has developed an approach that combines artificial intelligence (AI) with more traditional mechanistic models, to predict the yields and critical quality attributes of antibody products.
“These sorts of tools might help [drug developers] develop processes faster and explore different process conditions without exhaustive experiments,” explains Cleo Kontoravdi, PhD, an associate professor in biosystems engineering at Imperial College. “And, for manufacturers, our work can help them with regulatory approval where they need to show they have a good handle on [product] quality and reproducibility.” ....

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Problems at biggest vaccine maker leave world short on Covid shots | India News

Around the world, from Bangladesh to Nepal to Rwanda, vulnerable hotspots have been grappling with stalled Covid-19 vaccination programs as they run out of doses. Many of those shortages can be traced back to a single company: The Serum Institute of India.
The world’s largest vaccine maker, Serum was last year named a top supplier of Covid shots to Covax, the World Health Organization-backed initiative aimed at securing an equitable global rollout. But the Indian company has been dogged by setbacks, from a ban on exports to a factory fire, that have hampered its ability to fill orders.
Covax has pledged to send shots to some 92 countries, but has so far received only 30 million of the minimum 200 million doses it ordered from Serum, which was to provide the bulk of its early supply. Serum’s travails have now become a key illustration of how the effort to inoculate against Covid has failed the developing world and a cautionary tale for becoming over-reliant on one man ....

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Problems at Biggest Vaccine Maker Leave World Short on Covid Shots

Problems at Biggest Vaccine Maker Leave World Short on Covid Shots
Bloomberg
4 hrs ago
Chris Kay and P R Sanjai
(Bloomberg) Around the world, from Bangladesh to Nepal to Rwanda, vulnerable hotspots have been grappling with stalled Covid-19 vaccination programs as they run out of doses. Many of those shortages can be traced back to a single company: The Serum Institute of India.
The world’s largest vaccine maker, Serum was last year named a top supplier of Covid shots to Covax, the World Health Organization-backed initiative aimed at securing an equitable global rollout. But the Indian company has been dogged by setbacks, from a ban on exports to a factory fire, that have hampered its ability to fill orders. ....

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Serum Institute: Problems at biggest vaccine maker - Serum Institute - leave world short on Covid shots

The Indian company has been dogged by setbacks, from a ban on exports to a factory fire, that have hampered its ability to fill orders. ....

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