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Overnight lane closures for road widening to start in Berkeley Co.


Overnight lane closures for road widening to start in Berkeley Co.
The Berkeley County Government says overnight road closures will begin Sunday night for phase two of the Clements Ferry Road Widening Project. (Source: Gray News/File)
By Chloe Rafferty | January 10, 2021 at 10:57 AM EST - Updated January 10 at 10:57 AM
BERKELEY COUNTY, S.C. (WCSC) - The Berkeley County Government says overnight road closures will begin Sunday night for phase two of the Clements Ferry Road Widening Project.
They say the closures along Clements Ferry Road will begin 8 p.m. Sunday and will occur nightly from 8 p.m. to 6 a.m. through Thursday. ....

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The digital revolution in eye-care: Are measures of visual function with modern displays equivalent to those from legacy tests?


Summary
Digital displays are ubiquitous in modern daily life. In many areas, such displays have replaced, or are in the process of replacing, conventional items such hard-copy books, analogue watches and car dashboard gauges. Similarly, many clinical vision tests are increasingly being presented on a range of modern visual displays ranging from LCD monitors to OLED displays for use in the home and clinical settings; a move away from antiquated (but still regularly used) non-digital systems. Measurements obtained from these devices are relied upon by clinicians to make decisions about patient wellbeing and treatment, and therefore need to be fit-for-purpose to meet the challenges of modern-day clinical practice. Despite the positive move to more modern platforms, it is still imperative that legacy measures, often collected over decades, can be incorporated into the determination of disease stability or otherwise. Thus, there is a need to ensure that the benefits of novel platfo ....

United Kingdom , United States , East Sussex , Northern Ireland , City Of , Florida State University , Nigel Irwin , Natalie Klempel , Prawej Ansari , Declan Mckenna , William Crowe , Yasser Abdel Wahab , Karl Smith , Ahmed Abuelhana , Bryan Lafferty , Bryan Kelsey , Linden Ashfield , Kathryn Burnett , Dawood Khan , Peter Flatt , Catriona Kelly , Colum Walsh , Charlotte Zoe Angel , Kieran Odonnell , Neville Mcclenaghan , Poonam Singh Nigam ,

Exploring G Protein-Coupled Receptor signaling in pancreatic islets as targets for diabetes and its complications


Summary
The prevalence of type 2 diabetes has risen dramatically during recent decades and there is an urgent need to develop new approaches for therapeutic treatment that provide a combination of benefits, with fewer side effects and better patient outcomes. When diabetes is not managed, it can lead to serious complications including cardiovascular disease (CVD), stroke, blindness, kidney disease and premature mortality. CVD is a major cause of death and disability in diabetes, accounting for 52% of fatalities in those with type 2 diabetes.
New treatments are necessary due to the increasing prevalence of diabetes and its complications. In recent years, therapies that target the actions of glucagon-like peptide-1 (GLP-1) which stimulate insulin secretion through activation of beta cell G protein-coupled receptors (GPCRs) have been successful. This has resulted in substantial interest in targeting other islet GPCRs for diabetic therapies [1-3]. GPCRs are a superfamily of tr ....

United Kingdom , United States , Florida State University , East Sussex , Northern Ireland , City Of , Nigel Irwin , Natalie Klempel , Prawej Ansari , Declan Mckenna , William Crowe , Yasser Abdel Wahab , Karl Smith , Ahmed Abuelhana , Bryan Lafferty , Bryan Kelsey , Linden Ashfield , Kathryn Burnett , Dawood Khan , Peter Flatt , Catriona Kelly , Colum Walsh , Charlotte Zoe Angel , Kieran Odonnell , Neville Mcclenaghan , Poonam Singh Nigam ,

Detailed text transcripts for TV channel - DW - 20190115:12:20:00

Place in the round of sixteen they drew one all with thailand who also progressed the next round despite firing their coach early in the tournament. now a twist on the tradition of champion sports teams in the u.s. who are invited to the white house for photos and the cullen area device of its top rate cooking staff in the midst of a partial government shutdown the dishes of the day for the college football champions from clements in university were fast food burgers pizza and other great american food as the host of the event donald trump put it the junk food loving president also made it known that he picked up the bill a number of white house staffers including some in the kitchen are out of work during the shutdown. of all to have been announcing a major commitment to america gary hart has that story and a whole lot more that s right if you are now is that it wants to invest eight hundred million dollars in his u.s. production facilities a move expected to counteract negative effec ....

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Detailed text transcripts for TV channel - DW - 20190107:11:32:00

Him that made it all happen stolen down in twenty thirteen make upload of the song to you tube and immediately won over hearts across the globe. they put their first album together here in clements in a bines room at his parents place sad necessary it was a top twenty hit in germany. their studio set up might have changed since but. where they work has not. i think up a song and then i walked over to phillip so proud of myself. i ve got a new song. let me come up with a beat and try to. it s ....

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