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Astellas wins first approval of Vyloy in gastric cancer in Japan

Japan’s Ministry of Health, Labor and Welfare approved Astellas Pharma Inc.’s Vyloy (zolbetuximab) to treat a type of advanced gastric cancer on March 26, making it the first anti-claudin 18.2 monoclonal antibody to gain regulatory clearance worldwide. ....

Astellas Pharma Inc , Japan Ministry Of Health , Astellas Pharma , Astellas Pharma Inc , Gastric Cancer , Claudin18 2 , Cldn18 2 , Her2 Negative , Asia Pacific , Monoclonal Antibody , Bioworld Asia ,

CMG901 Elicits Responses in CLDN18.2-Expressing Gastric/GEJ Cancer

CMG901 induced responses with a manageable toxicity profile in patients with CLDN18.2-positive gastric or gastroesophageal junction cancer, according to updated data from the dose-expansion phase of the phase 1 KYM901 study. ....

Keymed Biosciences , Astellas Pharma , Merck Serono , Junshi Biosciences , Sun Yat Sen University Cancer Center , Bristol Myers Squibb , Ruand Y , Zhangd S , Cldn18 2 , Gastric Cancer , Gastroesophageal Cancer , Gej Cancer , Asco Plenary Series , November Asco Plenary Series , Phase 1 Kym901 Trial , Antibody Drug Conjugate ,

CLDN18.2 Testing May Influence Advances in the Gastric Cancer Treatment Paradigm

Kevin M. Waters, MD, PhD, discusses key findings from a study that reinforced the rationale for Claudin18.2 testing, the prevalence of this protein in gastric cancers, and how this potential therapeutic target represents the evolving role of pathology in cancer diagnosis and care. ....

United States , Los Angeles , Laboratory Medicine At Cedars , Sinai Medical Center , Clinical Pathology Residency Program , Laboratory Medicine , Cedars Sinai Medical Center , Cedars Sinai , Claudin18 2 , Cldn18 2 , Spotlight Trial ,