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Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered. ....

Kazuhiro Fukumura , Michael Sattler , Akila Mayeda , Fujita Health University , Fujita Health , Cell Reports , N Vitro , N Vivo ,

Cryo-EM reveals structure of key enzyme involved in protein production

Transfer RNAs (tRNAs) are among the most common types of RNA in a cell and are indispensable for protein production in all known organisms. ....

Samoil Sekulovski , Danielle Ellis , Simon Trowitzsch , Julius Maximilians University , Institute Of Biochemistry , Goethe University , Institute Of Biochemistry At Goethe University , Institute Of Biochemistry At Goethe University Frankfurt , Goethe University Frankfurt , Structural Biology , Genetic Information , Pontocerebellar Hypoplasia ,

MyJournals.org - Science - 'Molecules, Vol. 28, Pages 4460: Group I Intron as a Potential Target for Antifungal Compounds: Development of a Trans-Splicing High-Throughput Screening Strategy' (Molecules)

MyJournals.org - Science - Molecules, Vol. 28, Pages 4460: Group I Intron as a Potential Target for Antifungal Compounds: Development of a Trans-Splicing High-Throughput Screening Strategy (Molecules) ....

Rans Splicing , High Throughput ,

Judge ends landmark half-century old Hartford police consent decree; officials vow work is not done

In a letter to Members of the Court of Common Council about the Dooley ruling, Mayor Luke Bronin said that her decision in dissolving the consent decree emphasized the significant work that the city has done, the progress that the city has made and she found the claims made by the plaintiffs in their most recent motion were without merit. ....

City Of Hartford , United States , Karia Dooley , Marilyne Rossetti , Corrie Betts , Luke Bronin , Thomas Vaughan , Hartford City Council , Police Department , Common Council , City Council , Police Review Board , Police Accountability Review Board , Associated Press , Hartford Police Department , Judge Kari , Police Chief Thomas Vaughan , Civilian Police Review Board , Associated Press Monday , Greater Hartford , Civil Rights , Onnecticut News , Hartford News , Police Department , Hartford Police Department ,

New model contributes to the understanding of huge variety of genome sizes in nature

A new model developed at Tel Aviv University offers a possible solution to the scientific question of why neutral sequences, sometimes referred to as "junk DNA", are not eliminated from the genome of living creatures in nature and continue to exist within it even millions of years later. ....

Gil Loewenthal , Emily Henderson , Cancer Research , Faculty Of Life Sciences , Shmunis School Of Biomedicine , Tel Aviv University , Itay Mayrose Faculty Of Life Sciences , Tal Pupko , Shmunis School , Life Sciences , Itay Mayrose , Industry Focus , Junk Dna ,