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Blocking TIM-3 checkpoint molecule promotes antitumor immune response in diffuse intrinsic stem glioma

Researchers from Cima and the Clínica Universidad de Navarra, together with the international cooperative group Diffuse Midline Glioma (DMG-ACT), have confirmed that blocking an immune checkpoint molecule reduces the tumor and prolongs survival in animal models of the most aggressive childhood cancer. This research, carried out at the Cancer Center Clínica Universidad de Navarra, shows that inhibition of TIM-3 promotes the immune memory of diffuse intrinsic stem glioma (DIPG) and improves the prognosis of the disease.

Spain
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Marta-alonso
Iker-ausejo-mauleon
Cancer-center-cl
Cima-university-of-navarra
European-research-council
Cima-solid-tumor-program
Spanish-association-against-cancer
Adey-foundation
Pablo-ugarte-association

Researchers in Spain search for better immunotherapy mixture to fight liver cancer

RESEARCHERS at Navarra's Cima University believe that a new combination of immunotherapy treatment could be used to fight liver cancer, and are testing

Ignacio-melero
Navarra-cima-university
Cima-university

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

New-york
United-states
Teijeira
Galicia
Spain
Spanish
Lily-ramsey
Carmen-ochoa
Ignacio-melero
Saray-garasa
Amaia-lujambio
Cancer-center-cl

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Acute myeloid leukemia (AML) is a very aggressive disease in which cells proliferate abnormally, invading the bone marrow and interfering with normal blood cell production. It is the most common acute leukemia in adults with the worst prognosis.

United-states
Spain
Spanish
American
Maria-dolores-odero
Lily-ramsey
Carmen-mateos
Nerea-marcotegui
Jose-angel-martinez-climent
Vicente-fresquet
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