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Biologists discover a previously unknown way that the immune system detects viruses

Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs. ....

Nandan Gokhale , Russell Vance , Matthew Daugherty , Rimjhim Agarwal , Patrick Mitchell , Megan Craig , Christina Yap , Lennice Castro , Ram Savan , Christopher Beierschmitt , Elizabeth Turcotte , Jessie Kulsuptrakul , Andrew Ryan , Jennifer Hyde , Brian Tsu , Matt Daugherty , Elizabeth Fay , University Of California San Diego , Department Of Molecular Biology , University Of Washington , School Of Biological Science Matt Daugherty , California San Diego , Biological Science Matt Daugherty , Sofia Delgado Rodriguez ,

Scientists Discover COVID-19 Trip Wire in Immune System

Scientists Discover COVID-19 Trip Wire in Immune System
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Brian Tsu , Rimjhim Agarwal , Jennifer Hyde , Elizabeth Fay , Patrick Mitchell , Jessie Kulsuptrakul , Christina Yap , Elizabeth Turcotte , Matthew Daugherty , Nandan Gokhale , Lennice Castro , Russell Vance , Ram Savan , Andrew Ryan , Christopher Beierschmitt , University Of Washington , University Of California San Diego , Department Of Molecular Biology , School Of Biological Science Matt Daugherty , California San Diego , Biological Science Matt Daugherty , Sofia Delgado Rodriguez ,

Immune system sets 'tripwire' to protect against viruses

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IMAGE: A new study by UC San Diego biologists has revealed insights on the intricate, adaptive mechanisms of a protective system employed by the cells of mammalian immune systems. These defenses.
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Credit: Brian Tsu, Daugherty Lab, UC San Diego
Scientists are opening new windows into understanding more about the constantly shifting evolutionary arms race between viruses and the hosts they seek to infect. Host organisms and pathogens are in a perennial chess match to exploit each other s weaknesses.
Such research holds tantalizing clues for human health since the immune system is on constant alert to deploy counter measures against new viral attacks. But unleashing too much of a defensive response can lead to self-inflicted tissue damage and disease. ....

Christopher Beierschmitt , Brian Tsu , Rimjhim Agarwal , Andrew Ryan , Matt Daugherty , Chris Beierschmitt , Patrick Mitchell , Andy Ryan , University Of California San Diego , National Institutes Of Health , National Science Foundation , Pew Biomedical Scholars Program , Hellman Fellows Program , California San Diego , Biological Sciences , Assistant Professor Matt Daugherty , National Institutes , Jane Coffin Childs Memorial Fund , Medical Research , பிரையன் ட்ஸ்யூ , ரிம்ஜிம் அகர்வால் , ஆண்ட்ரூ ரியான் , மேட் ட Aug ஹெர்டி , பேட்ரிக் மிட்செல் , ஆண்டி ரியான் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா சான் டியாகோ ,