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Frontiers | Lipidomics Reveals That Rice or Flour as a Single Source of Carbohydrates Cause Adverse Health Effects in Rats

The type of diet is very important for the maintenance of health and nutrition. How does the sole source of carbohydrate from rice- or flour-based diet effect blood sugar has not been clearly answered for a long time. In order to explore the effects of these diets, sixty SD rats were randomly divided into three groups: control group (C group, AIN-93, standard diet), rice diet group (R group), and flour diet group (F group). All the rats were fed for 7 weeks in total by the assigned diets for 4 weeks (stage 1, S1) and all by AIN-93 diet for 3 weeks (stage 2, S2). The body weight of all the rats were monitored and serum samples were taken for testing blood glucose, biochemical indicators and untargeted lipidome. It was found that both rice and flour-based diets caused weight gain, but the flour diet had a significant increase in blood sugar and low-density lipoprotein (LDL), while a significant decrease in albumin (ALB) and triglycerides (TG). Twenty-three and 148 lipids were changed by ....

South Korea , United States , Zhang Qi , Liu Xiaobing , J Vitam Nutr , Oresicm Lipidomics , Chim Acta , Liu Shuai , J Clin Nutr , Buechlerc Lipidomic , Dias Novaes , Avanti Polar Lipids Inc , Co Ltd , Chinese Nutrition Society , Merck Company Darmstadt , Joint Health , Public Health , Ethics Committee Of National Institute For Nutrition , Vital River Laboratory Animal Technology Co Ltd , American Institute Of Nutrition , Waters Company Milford , Technology Commission , Hitachi Company Tokyo , American Institute , Hitachi Company , Waters Company ,

Frontiers | Systems Immunology Analysis Reveals the Contribution of Pulmonary and Extrapulmonary Tissues to the Immunopathogenesis of Severe COVID-19 Patients


2Luebeck Institute of Experimental Dermatology, University of Luebeck, Luebeck, Germany
3General Surgery Department, Tawam Hospital, SEHA, Al Ain, United Arab Emirates
4Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates
5Department of Genetics and Molecular Biology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates
6Department of Respiratory Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates
7Meakins-Christie Laboratories, McGill University, Montreal, QC, Canada
8Division of Surgery and Interventional Science, University College London, London, United Kingdom
As one of the current global health conundrums, COVID-19 pandemic caused a dramatic increase of cases exceeding 79 million and 1.7 million deaths worldwide. Severe presentation of COVID-19 is characterized by cytokine storm and chronic inflammation resulting in multi-organ dysfunction. Curre ....

South Korea , Ash Shariqah , United Arab Emirates , Abu Dhabi , Abuz Aby , Gholamrezanezhada Extrapulmonary , Clin Chim Acta , Acta Haematologica , Cortijoj Mucins , Argininosuccinate Synthetase , Minghimr Interactivenn , Albrechtm Altanalyze , Fitzeg Hsp , Deutsche Forschungsgemeinschaft , Lysophosphatidylcholine Acyltransferase , J Physiol Endocrinol , Abu Dhabi Health , Research Ethics , Research Ethics Committee , Nuclear Receptors , German Research Foundation Under Germany Excellence Strategy , World Health Organization , Sharjah Research Academy Grant , University Of Sharjah , Their Association With Disease Outcomes In Severe , Dubai Scientific Research Ethics Committee ,