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Universal hope for hemophilia | UNC-Chapel Hill

Current hemophilia treatments have limitations for a significant number of patients. That’s why Carolina-connected startup GeneVentiv Therapeutics is developing the first universal, single-dose gene therapy for all types of hemophilia, including the toughest cases. ....

United States , New Jersey , North Carolina , University Of North Carolina , Jude Samulski , Chengwen Li , Drug Administration , Technology Development Center Investor Ready , National Hemophilia Foundation , Kickstart Venture Services , Gene Therapy Center , Geneventiv Therapeutics , Damon Race , Chapel Hill , Therapy Center , Orphan Drug Designation , Kickstart Venture , Innovate Carolina ,

Dexamethasone administration at a late time point could enhance transgene expression

Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors. ....

Terencer Flotte , Chengwen Li , Emily Henderson , University Of North Carolina At Chapel Hill , Human Gene , Human Gene Therapy , North Carolina , Chapel Hill , Anti Inflammatory , Gene Therapy ,