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Light show in living cells

<p>Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge - especially in living cells, as the required fluorescent labelling had to be individually attached to each protein. The research group led by Stefan Kubicek at CeMM has now overcome this hurdle: With a method called "vpCells," it is possible to label many proteins simultaneously, using five different fluorescent colours. This automated high-throughput approach, aided by AI-assisted image recognition, opens up entirely new applications in various disciplines, from fundamental cell biology to drug discovery. The study has been published in the journal <em>Nature Cell Biology</em> (DOI: 10.1038/s41556-024-01407-w), and the related images are available at <em>vpcells.cemm.at</em>.</p>
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Stuart Schreiber , Maria Ciobanu , Marton Siklos , Viktoriia Kartysh , Tatjana Tomek , Stefan Kubicek , Thomas Jenuwein , Anna Koren , Stefan Bernhardt , Andreas Reicher , Monika Malik , European Union Horizon , Method Of Research , Boehringer Ingelheim , Austrian Science Fund , Technology Fund , Research Center , Broad Institute Of Harvard , European Research Council , Vienna University Of Technology , Pr Communications , Cemm Research Center , Molecular Medicineof The Austrian Academy Of Sciences , Austrian Academy Of Sciences , Christian Doppler Laboratory For Chemical Epigenetics , Nature Cell Biology ,

New inhibitor shows promise in combating advanced prostate cancer

More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. ....

Pharmazeutische Wissenschaften , Eric Metzger , Manfred Jung , Department Of Urology , Nature Communications , University Of Freiburg , Freiburg University Medical Center , Medical Faculty , Professor Roland Sch , Academic Director , Professor Manfred Jung , Chemical Epigenetics , Prostate Cancer , Bladder Cancer ,

Newly developed inhibitor shows potential for prostate cancer

Newly developed inhibitor shows potential for prostate cancer
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Sheng Wang , Eric Metzger , Manfred Jung , Pharmazeutische Wissenschaften , Nature Communications , University Of Freiburg , Department Of Urology , Freiburg University Medical Center , Medical Faculty , Professor Roland Sch , Academic Director , Professor Manfred Jung , Chemical Epigenetics ,

Proxygen Announces Formation of Scientific Advisory Board

Proxygen Announces Formation of Scientific Advisory Board
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United States , Gottfried Wilhelm , Brenda Schulman , Bernd Boidol , Stefan Kubicek , Stuart Schreiber , Georg Winter , Jude Children Research Hospital , Boehringer Ingelheim , Merck Co , Christian Doppler Laboratory For Chemical Epigenetics , Records Of Founding Biopharma Companies , Molecular Discovery Program , Austrian Academy Of Sciences , Research In Dr , American Academy Of Arts , Hospital Cancer Center , Merck Kga , Head Of Cemm Molcular Discovery Program , Merck Kgaa , Max Planck Institute , Broad Institute Of Harvard , Research Center , National Academy Of Sciences , Diabetes Research Foundation , University Of Texas Md Anderson Cancer Center ,

LMU: New research network from LMU and TUM for next-generation active ingredients | India Education | Latest Education News | Global Educational News

LMU: New research network from LMU and TUM for next-generation active ingredients | India Education | Latest Education News | Global Educational News
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Stefan Engelhardt , Thomas Carell , Technical University Of Munich , Institute Of Chemical Epigenetics , German Federal Ministry Of Education , Institute Of Pharmacology , German Federal Ministry , Nucleic Acid Therapeutics Munich , Free State , Professor Thomas Carell , Chemical Epigenetics , Professor Stefan Engelhardt , Technical University ,