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Reconstruction of a genome-scale metabolic model and in-silico flux analysis of Aspergillus tubingensis: a non-mycotoxinogenic citric acid-producing fungus | Biotechnology for Biofuels and Bioproducts

Aspergillus tubingensis is a citric acid-producing fungus that can utilize sugars in hydrolysate of lignocellulosic biomass such as sugarcane bagasse and, unlike A. niger, does not produce mycotoxins. To date, no attempt has been made to model its metabolism at genome scale. Here, we utilized the whole-genome sequence (34.96 Mb length) and the measured biomass composition to reconstruct a genome-scale metabolic model (GSMM) of A. tubingensis DJU120 strain. The model, named iMK1652, consists of 1652 genes, 1657 metabolites and 2039 reactions distributed over four cellular compartments. The model has been extensively curated manually. This included removal of dead-end metabolites and generic reactions, addition of secondary metabolite pathways and several transporters. Several mycotoxin synthesis pathways were either absent or incomplete in the genome, providing a genomic basis for the non-toxinogenic nature of this species. The model was further refined based on the experimenta ....

United States , United Kingdom , University Of Leeds Next Generation Sequencing Facility , Chemglass Life Sciences , University Of York Technology Facility , Biolog Inc , Megazyme International Ireland Ltd , Lightrun Tube , Eurofins Genomics , York Technology Facility , Leeds Next Generation Sequencing Facility , Illumina Hiseq , Assay Kit , Thermo Fisher Scientific ,

World Travelers Feel the Spiritual Side of Shen Yun

PHILADELPHIA, Pa. Once again the Merriam Theater hosted Shen Yun Performing Arts to an audience ready to be entertained. . ....

United States , Shen Yun , Mary Zhang , Kirt Titchenell , Alan Durham , Weiyong Zhu , Chemglass Life Sciences , Merriam Theater , Shen Yun Performing Arts , Times Photo , Epoch Times , The Epoch Times ,

Bio-Reaction Tubes Market Future Demand, Market Analysis and Outlook to 2027

Bio-Reaction Tubes Market Future Demand, Market Analysis and Outlook to 2027
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Schlenk Flasks Market By Consumption Overview, Trends and Growth Forecast 2021 to 2027

Schlenk Flasks Market By Consumption Overview, Trends and Growth Forecast 2021 to 2027
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United States , Republic Of , Saudi Arabia , South Korea , Wilmad Labglass , Schlenk Flasksmarket , Co Ltd , Biotechnology Companies , Schlenk Flasks Development Trend Analysis , Kemtech America Inc , Chemglass Life Sciences , Life Sciences , Strem Chemical Inc , Pace Glass Inc , Research Institutions , Schlenk Flasks , Flasks Market , Schlenk Flasks Market , Exclusive Offer , Sample Copy , Global Schlenk Flasks , North America , Questions Answered In The Report , Know More , Global Schlenk Flasks Market , Schlenk Flasks Market Data ,

Spinner Flasks Market Growing Demands, Trends and Business Outlook 2021 to 2027

Spinner Flasks Market Growing Demands, Trends and Business Outlook 2021 to 2027
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Wilmad Labglass , Biotechnology Companies , Electron Microscopy Sciences , Stemcell Technologies Inc , Chemglass Life Sciences , Life Sciences , Bellco Glass Inc , Research Institutions , Latest Released , Spinner Flasks , Global Spinner Flasks , Microscopy Sciences , Including Full , Spinner Flasks Market , End User , Quarter End Discount , Complete Report , Sales Estimation , Historical Revenue , Market Share , Demand Determinants ,